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erlin2.L ER lipid raft associated 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 495100, updated on 17-Aug-2024

Summary

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Official Symbol
erlin2.L
Official Full Name
ER lipid raft associated 2 L homeolog
Primary source
Xenbase:XB-GENE-950149
Locus tag
XELAEV_18018502mg
See related
EnsemblRapid:ENSXLAG00005000839
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
spfh2; erlin2; spfh2-A; erlin2-a; erlin2-b
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Genomic context

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Location:
chromosome: 3L
Exon count:
13
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (126040685..126065379, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (110645737..110667113, complement)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor A2 L homeolog Neighboring gene pyridoxal phosphate binding protein L homeolog Neighboring gene zinc finger protein 703 L homeolog Neighboring gene protein spinster homolog 1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility. Iioka H, et al. Nat Cell Biol, 2007 Jul. PMID 17558393
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
erlin-2-A
Names
Endoplasmic reticulum lipid raft-associated protein 2-A
SPFH domain-containing protein 2-A
Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2-A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094800.1 → NP_001088269.1  erlin-2-A

    See identical proteins and their annotated locations for NP_001088269.1

    Status: PROVISIONAL

    Source sequence(s)
    BC084273
    UniProtKB/Swiss-Prot
    Q5XH03
    UniProtKB/TrEMBL
    A0A8J1MHC6, A0A974DD31
    Related
    ENSXLAP00005002493.1, ENSXLAT00005002539.1
    Conserved Domains (1) summary
    cd03406
    Location:16 → 308
    SPFH_like_u3; Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    126040685..126065379 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041585190.1 → XP_041441124.1  erlin-2-A isoform X1

    UniProtKB/Swiss-Prot
    Q5XH03
    UniProtKB/TrEMBL
    A0A8J1MHC6, A0A974DD31
    Conserved Domains (1) summary
    cd03406
    Location:16 → 308
    SPFH_like_u3; Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

  2. XM_041585191.1 → XP_041441125.1  erlin-2-A isoform X2

    UniProtKB/TrEMBL
    A0A8J1MJA5
    Conserved Domains (1) summary
    cl19107
    Location:16 → 186
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XH03.1 GenPept UniProtKB/Swiss-Prot:Q5XH03

Gene LinkOut

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