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atg4c.S autophagy related 4C, cysteine peptidase S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 495080, updated on 4-Nov-2024

Summary

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Official Symbol
atg4c.S
Official Full Name
autophagy related 4C, cysteine peptidase S homeolog
Primary source
Xenbase:XB-GENE-941092
Locus tag
XELAEV_18025135mg
See related
EnsemblRapid:ENSXLAG00005012516 AllianceGenome:Xenbase:XB-GENE-941092
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
apg4c; atg4c
Summary
Predicted to enable cysteine-type peptidase activity. Predicted to act upstream of or within autophagy and protein delipidation. Predicted to be located in cytoplasm. Orthologous to human ATG4C (autophagy related 4C cysteine peptidase). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See atg4c.S in Genome Data Viewer
Location:
chromosome: 4S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (65951261..65979645, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (59769811..59798220, complement)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene ALG6, alpha-1,3-glucosyltransferase S homeolog Neighboring gene forkhead box D3 S homeolog Neighboring gene dedicator of cytokinesis 7 S homeolog Neighboring gene angiopoietin like 3 S homeolog Neighboring gene KN motif and ankyrin repeat domains 4 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables cysteine-type peptidase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein-phosphatidylethanolamide deconjugating activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within autophagy IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within autophagy ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within protein delipidation ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cysteine protease ATG4C
Names
ATG4 autophagy related 4 homolog C
autophagy-related protein 4 homolog C
NP_001088249.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094780.1 → NP_001088249.1  cysteine protease ATG4C

    See identical proteins and their annotated locations for NP_001088249.1

    Status: PROVISIONAL

    Source sequence(s)
    BC084245
    UniProtKB/Swiss-Prot
    Q5XH30
    UniProtKB/TrEMBL
    A0A974HM28
    Related
    ENSXLAP00005036724.1, ENSXLAT00005037633.1
    Conserved Domains (1) summary
    pfam03416
    Location:78 → 387
    Peptidase_C54; Peptidase family C54

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    65951261..65979645 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XH30.1 GenPept UniProtKB/Swiss-Prot:Q5XH30

Gene LinkOut

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