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ing5.S inhibitor of growth family member 5 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 495052, updated on 4-Nov-2024

Summary

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Official Symbol
ing5.S
Official Full Name
inhibitor of growth family member 5 S homeolog
Primary source
Xenbase:XB-GENE-17329997
Locus tag
XELAEV_18029878mg
See related
EnsemblRapid:ENSXLAG00005029926 AllianceGenome:Xenbase:XB-GENE-17329997
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable chromatin binding activity; metal ion binding activity; and methylated histone binding activity. Predicted to act upstream of or within chromatin organization; positive regulation of apoptotic signaling pathway; and regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human ING5 (inhibitor of growth family member 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ing5.S in Genome Data Viewer
Location:
chromosome: 5S
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5S NC_054380.1 (113354111..113375114, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5S NC_030733.1 (106598284..106617472, complement)

Chromosome 5S - NC_054380.1Genomic Context describing neighboring genes Neighboring gene diacylglycerol kinase delta S homeolog Neighboring gene D-2-hydroxyglutarate dehydrogenase S homeolog Neighboring gene deoxythymidylate kinase S homeolog Neighboring gene autophagy related 4B, cysteine peptidase S homeolog Neighboring gene THAP domain containing 4 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables methylated histone binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
inhibitor of growth protein 5; uncharacterized protein LOC495052

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054380.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    113354111..113375114 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041564967.1 → XP_041420901.1  inhibitor of growth protein 5

    UniProtKB/TrEMBL
    A0A974CSG0, A0A974CSP7, Q5XH71
    Related
    ENSXLAP00005089603.1, ENSXLAT00005091272.1
    Conserved Domains (2) summary
    COG5034
    Location:1 → 230
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd16863
    Location:12 → 104
    ING_ING5; Inhibitor of growth (ING) domain of inhibitor of growth protein 5 (ING5)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001094755.1: Suppressed sequence

    Description
    NM_001094755.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

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