cnot6l.S CCR4-NOT transcription complex subunit 6-like S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: cnot6l.S
Official Full Name: CCR4-NOT transcription complex subunit 6-like S homeolog
Primary source: Xenbase:XB-GENE-977554
Locus tag: XELAEV_18009534mg
See related: EnsemblRapid:ENSXLAG00005017424 AllianceGenome:Xenbase:XB-GENE-977554
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ccr4b; cnot6l; cnot6l-a; cnot6l-b
Summary: Predicted to enable metal ion binding activity and poly(A)-specific ribonuclease activity. Predicted to act upstream of or within mRNA processing and regulation of gene expression. Predicted to be located in cytoplasm and nucleus. Predicted to be part of CCR4-NOT complex. Orthologous to human CNOT6L (CCR4-NOT transcription complex subunit 6 like). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 1S

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1S	NC_054372.1 (71410141..71469022, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1S	NC_030725.1 (70835388..70890636, complement)

Chromosome 1S - NC_054372.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables exonuclease activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables poly(A)-specific ribonuclease activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nuclear-transcribed mRNA poly(A) tail shortening	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of translation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulatory ncRNA-mediated gene silencing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of CCR4-NOT complex	IEA Inferred from Electronic Annotation more info
part_of CCR4-NOT complex	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: CCR4-NOT transcription complex subunit 6-like-B

Names: CCR4-NOT transcription complex, subunit 6-like

NP_001088222.1

EC 3.1.13.4

XP_041431958.1

EC 3.1.13.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094753.1 → NP_001088222.1 CCR4-NOT transcription complex subunit 6-like-B

See identical proteins and their annotated locations for NP_001088222.1

Status: PROVISIONAL

Source sequence(s)

BC084200

UniProtKB/Swiss-Prot

Q5XH73

UniProtKB/TrEMBL

A0A974I0I0

Related

ENSXLAP00005051495.1, ENSXLAT00005052657.1

Conserved Domains (4) summary

cd10312
Location:186 → 533

Deadenylase_CCR4b; C-terminal deadenylase domain of CCR4b, also known as CCR4-NOT transcription complex subunit 6-like

sd00033
Location:53 → 75

LRR_RI; leucine-rich repeat [structural motif]

pfam12799
Location:51 → 91

LRR_4; Leucine Rich repeats (2 copies)

pfam13855
Location:51 → 132

LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

71410141..71469022 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041576024.1 → XP_041431958.1 CCR4-NOT transcription complex subunit 6-like-B isoform X1

UniProtKB/TrEMBL

A0A1L8HMJ8, A0A974I0V0

Related

ENSXLAP00005051484.1, ENSXLAT00005052646.1

Conserved Domains (3) summary

cd10312
Location:186 → 533

Deadenylase_CCR4b; C-terminal deadenylase domain of CCR4b, also known as CCR4-NOT transcription complex subunit 6-like

COG4886
Location:32 → 140

LRR; Leucine-rich repeat (LRR) protein [Transcription]

sd00031
Location:33 → 52

LRR_1; leucine-rich repeat [structural motif]