nubp1.L nucleotide binding protein 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: nubp1.L
Official Full Name: nucleotide binding protein 1 L homeolog
Primary source: Xenbase:XB-GENE-992731
Locus tag: XELAEV_18045130mg
See related: EnsemblRapid:ENSXLAG00005020360 AllianceGenome:Xenbase:XB-GENE-992731
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: nbp; nbp1; nubp1; nubp1-a; nubp1-b
Summary: Predicted to enable iron-sulfur cluster binding activity. Predicted to act upstream of or within iron-sulfur cluster assembly. Predicted to be located in cytosol. Is expressed in anatomical system; ectoderm; and pharyngeal arch. Orthologous to human NUBP1 (NUBP iron-sulfur cluster assembly factor 1, cytosolic). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 9_10L

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10L	NC_054387.1 (98932594..98948971, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	9_10L	NC_030740.1 (88349572..88365949, complement)

Chromosome 9_10L - NC_054387.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Effects of xNubp1 knockdown on the actin cytoskeleton are independent of RhoA localization and activation, suggesting that xNubp1 may have a direct role in the regulation of the actin cytoskeletonciliogenesis via regulation of the actin cytoskeleton.
Title: Xenopus laevis nucleotide binding protein 1 (xNubp1) is important for convergent extension movements and controls ciliogenesis via regulation of the actin cytoskeleton.

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables 4 iron, 4 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP-dependent FeS chaperone activity	IEA Inferred from Electronic Annotation more info
enables iron-sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables iron-sulfur cluster binding	ISS Inferred from Sequence or Structural Similarity more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within iron-sulfur cluster assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within iron-sulfur cluster assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: cytosolic Fe-S cluster assembly factor nubp1-A

Names: nucleotide binding protein 1 (MinD homolog)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094562.1 → NP_001088031.1 cytosolic Fe-S cluster assembly factor nubp1-A

See identical proteins and their annotated locations for NP_001088031.1

Status: PROVISIONAL

Source sequence(s)

BC106243

UniProtKB/Swiss-Prot

Q3KQF0, Q52KS7

UniProtKB/TrEMBL

A0A974C031, Q640D6

Related

ENSXLAP00005059651.1, ENSXLAT00005061100.1

Conserved Domains (2) summary

COG0489
Location:13 → 281

Mrp; Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster [Cell cycle control, cell division, chromosome partitioning]

pfam10609
Location:57 → 307

ParA; NUBPL iron-transfer P-loop NTPase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

98932594..98948971 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)