bcat1.L branched chain amino-acid transaminase 1, cytosolic L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: bcat1.L
Official Full Name: branched chain amino-acid transaminase 1, cytosolic L homeolog
Primary source: Xenbase:XB-GENE-5826143
Locus tag: XELAEV_18016616mg
See related: EnsemblRapid:ENSXLAG00005008212 AllianceGenome:Xenbase:XB-GENE-5826143
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: bcat1
Summary: Predicted to enable L-isoleucine-2-oxoglutarate transaminase activity; L-leucine-2-oxoglutarate transaminase activity; and L-valine-2-oxoglutarate transaminase activity. Predicted to act upstream of or within L-leucine biosynthetic process and L-valine biosynthetic process. Predicted to be located in mitochondrion. Orthologous to human BCAT1 (branched chain amino acid transaminase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 3L

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3L	NC_054375.1 (1603744..1625073, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	3L	NC_030728.1 (1574391..1595876, complement)

Chromosome 3L - NC_054375.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables L-isoleucine-2-oxoglutarate transaminase activity	IEA Inferred from Electronic Annotation more info
enables L-leucine-2-oxoglutarate transaminase activity	IEA Inferred from Electronic Annotation more info
enables L-valine-2-oxoglutarate transaminase activity	IEA Inferred from Electronic Annotation more info
enables branched-chain-amino-acid transaminase activity	IEA Inferred from Electronic Annotation more info
enables transaminase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within L-leucine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within L-valine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within amino acid biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within branched-chain amino acid biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within branched-chain amino acid metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: branched chain amino-acid transaminase 1, cytosolic L homeolog

Names: branched chain aminotransferase 1, cytosolic

NP_001087994.1

EC 2.6.1.42

XP_018106594.1

EC 2.6.1.42

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094525.1 → NP_001087994.1 branched chain amino-acid transaminase 1, cytosolic L homeolog

See identical proteins and their annotated locations for NP_001087994.1

Status: PROVISIONAL

Source sequence(s)

BC082673

UniProtKB/TrEMBL

A0A974DCA2, Q640F5

Related

ENSXLAP00005023601.1, ENSXLAT00005024306.1

Conserved Domains (2) summary

PRK13357
Location:41 → 392

PRK13357; branched-chain amino acid aminotransferase; Provisional

cd01557
Location:86 → 381

BCAT_beta_family; BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and ...