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dpm2.S dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 494631, updated on 4-Nov-2024

Summary

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Official Symbol
dpm2.S
Official Full Name
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit S homeolog
Primary source
Xenbase:XB-GENE-6255622
Locus tag
XELAEV_18041705mg
See related
EnsemblRapid:ENSXLAG00005014258 AllianceGenome:Xenbase:XB-GENE-6255622
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
dpm2; dpm2b; dpm2-a; dpm2-b
Summary
Predicted to enable enzyme regulator activity and glycosyltransferase activity. Predicted to act upstream of or within GPI anchor biosynthetic process; dolichol metabolic process; and protein glycosylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of dolichol-phosphate-mannose synthase complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Iu. Orthologous to human DPM2 (dolichyl-phosphate mannosyltransferase subunit 2, regulatory). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See dpm2.S in Genome Data Viewer
Location:
chromosome: 8S
Exon count:
4
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (35408018..35411781)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (35115153..35119004)

Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 S homeolog Neighboring gene collagen, type XXVII, alpha 1 S homeolog Neighboring gene phosphatidylinositol-4-phosphate 5-kinase-like 1 S homeolog Neighboring gene alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables enzyme regulator activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within dolichol metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of dolichol-phosphate-mannose synthase complex IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit S homeolog
Names
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001171707.1 → NP_001165178.1  dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit S homeolog

    See identical proteins and their annotated locations for NP_001165178.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082204
    UniProtKB/TrEMBL
    Q641S3
    Related
    ENSXLAP00005041809.1, ENSXLAT00005042836.1
    Conserved Domains (1) summary
    pfam07297
    Location:5 → 80
    DPM2; Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    35408018..35411781
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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