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HK2 hexokinase 2 [ Sus scrofa (pig) ]

Gene ID: 494561, updated on 17-Aug-2024

Summary

Official Symbol
HK2provided by VGNC
Official Full Name
hexokinase 2provided by VGNC
Primary source
VGNC:VGNC:98034
See related
Ensembl:ENSSSCG00000008261
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Broad expression in psoas major muscle (RPKM 9.8), lung (RPKM 7.6) and 6 other tissues See more
Orthologs
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Genomic context

See HK2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
18
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 3 NC_010445.4 (68155656..68231187, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 3 NC_010445.3 (71331772..71407448, complement)

Chromosome 3 - NC_010445.4Genomic Context describing neighboring genes Neighboring gene tachykinin receptor 1 Neighboring gene DNA polymerase epsilon 4, accessory subunit Neighboring gene glycine cleavage system H protein, mitochondrial-like Neighboring gene ssemaphorin 4F

Genomic regions, transcripts, and products

Expression

  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables D-glucose binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables fructokinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables glucokinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables mannokinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in glucose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intracellular glucose homeostasis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
hexokinase-2
Names
HK II
hexokinase II
hexokinase type II
skeletal muscle hexokinase II
NP_001116459.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001122987.1NP_001116459.1  hexokinase-2

    See identical proteins and their annotated locations for NP_001116459.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ432056
    UniProtKB/Swiss-Prot
    Q1W674
    UniProtKB/TrEMBL
    A0A4X1W0Z3, F1SNW8
    Related
    ENSSSCP00000008819.2, ENSSSCT00000009047.4
    Conserved Domains (3) summary
    PTZ00107
    Location:12460
    PTZ00107; hexokinase; Provisional
    pfam00349
    Location:21219
    Hexokinase_1; Hexokinase
    pfam03727
    Location:225459
    Hexokinase_2; Hexokinase

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010445.4 Reference Sscrofa11.1 Primary Assembly

    Range
    68155656..68231187 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)