pih1d2 PIH1 domain containing 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pih1d2provided by ZNC
Official Full Name: PIH1 domain containing 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-041212-54
See related: Ensembl:ENSDARG00000014849 AllianceGenome:ZFIN:ZDB-GENE-041212-54
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:101725
Summary: Acts upstream of or within axonemal dynein complex assembly. Predicted to be part of R2TP complex and ribonucleoprotein complex. Predicted to be active in cytoplasm. Is expressed in Kupffer's vesicle; floor plate; otic placode; and pronephric duct. Orthologous to human PIH1D2 (PIH1 domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (18133330..18162647, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (18202496..18226628, complement)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within axonemal dynein complex assembly	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within axonemal dynein complex assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in box C/D snoRNP assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in rRNA processing	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of R2TP complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: PIH1 domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008629.1 → NP_001008629.1 PIH1 domain-containing protein 2

See identical proteins and their annotated locations for NP_001008629.1

Status: PROVISIONAL

Source sequence(s)

BC086728

UniProtKB/Swiss-Prot

Q5PRB3

Related

ENSDARP00000017232.6, ENSDART00000012064.7

Conserved Domains (1) summary

cl00175
Location:51 → 321

alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007126.7 Reference GRCz11 Primary Assembly

Range

18133330..18162647 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_068213542.1 → XP_068069643.1 PIH1 domain-containing protein 2 isoform X3
XM_021481399.1 → XP_021337074.1 PIH1 domain-containing protein 2 isoform X2

UniProtKB/TrEMBL

A0A8M9QH82

Conserved Domains (1) summary

cl00175
Location:51 → 279

alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
XM_009291562.2 → XP_009289837.1 PIH1 domain-containing protein 2 isoform X1

UniProtKB/TrEMBL

A0A8M3B0W4

Conserved Domains (1) summary

cl00175
Location:51 → 318

alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.