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sqstm1 sequestosome 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 493277, updated on 18-Sep-2024

Summary

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Official Symbol
sqstm1provided by Xenbase
Official Full Name
sequestosome 1provided by Xenbase
Primary source
Xenbase:XB-GENE-5918988
See related
Ensembl:ENSXETG00000015913
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
p62
Orthologs
human mouse all
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Genomic context

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See sqstm1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
8
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (22196571..22205639, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (5429562..5438496)

Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene solute carrier family 7 (cationic amino acid transporter, y+ system), member 2, gene 2 Neighboring gene uncharacterized LOC105946789 Neighboring gene zona pellucida glycoprotein 4 Neighboring gene TBC1 domain family member 9B Neighboring gene ring finger protein 130

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC79491

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in autophagosome IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
sequestosome-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007893.1 → NP_001007894.1  sequestosome-1

    See identical proteins and their annotated locations for NP_001007894.1

    Status: PROVISIONAL

    Source sequence(s)
    BC080326
    UniProtKB/TrEMBL
    A0A803JYZ8, Q66KM6
    Related
    ENSXETP00000113256.1, ENSXETT00000106454.1
    Conserved Domains (3) summary
    cd06402
    Location:3 → 96
    PB1_p62; The PB1 domain is an essential part of p62 scaffold protein (alias sequestosome 1,SQSTM) involved in cell signaling, receptor internalization, and protein turnover. The PB1 domain is a modular domain mediating specific protein-protein interaction which ...
    cd02340
    Location:121 → 163
    ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
    cl21463
    Location:391 → 451
    UBA_like_SF; UBA domain-like superfamily

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    22196571..22205639 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018092044.2 → XP_017947533.1  sequestosome-1 isoform X1

    UniProtKB/TrEMBL
    A0A803JYZ8, F6TMS2
    Related
    ENSXETP00000034720.4, ENSXETT00000034720.5
    Conserved Domains (3) summary
    cd06402
    Location:3 → 96
    PB1_p62; The PB1 domain is an essential part of p62 scaffold protein (alias sequestosome 1,SQSTM) involved in cell signaling, receptor internalization, and protein turnover. The PB1 domain is a modular domain mediating specific protein-protein interaction which ...
    cd02340
    Location:121 → 163
    ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
    cl21463
    Location:395 → 455
    UBA_like_SF; UBA domain-like superfamily
Nucleotide Protein Strain
Heading Accession and Version

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