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DLG3 discs large MAGUK scaffold protein 3 [ Canis lupus familiaris (dog) ]

Gene ID: 491942, updated on 17-Aug-2024

Summary

Official Symbol
DLG3provided by VGNC
Official Full Name
discs large MAGUK scaffold protein 3provided by VGNC
Primary source
VGNC:VGNC:111435
See related
Ensembl:ENSCAFG00845015765
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See DLG3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
25
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (55853333..55908759)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (45713141..45768580)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (55080264..55135709)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (53822238..53877672)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (55153323..55208774)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene PDZ domain containing 11 Neighboring gene kinesin family member 4A Neighboring gene uncharacterized LOC119868453 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 2 Neighboring gene testis expressed 11 Neighboring gene microtubule-associated protein RP/EB family member 1-like Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables kinase binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in neuromuscular junction IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in postsynaptic density membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
disks large homolog 3
Names
discs, large homolog 3 (neuroendocrine-dlg, Drosophila)
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    55853333..55908759
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038450218.1XP_038306146.1  disks large homolog 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L3X8
    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:644822
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  2. XM_038450219.1XP_038306147.1  disks large homolog 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L3X8
    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:640818
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  3. XM_038450220.1XP_038306148.1  disks large homolog 3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L3X8, A0A8C0TLW5, A0A8I3NVY0
    Related
    ENSCAFP00845022454.1, ENSCAFT00845028540.1
    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:626804
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  4. XM_038450216.1XP_038306144.1  disks large homolog 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L3X8
    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:658836
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  5. XM_038450221.1XP_038306149.1  disks large homolog 3 isoform X5

    UniProtKB/TrEMBL
    A0A8C0L3K2, A0A8C0TP21, A0A8I3NW22
    Related
    ENSCAFP00845022502.1, ENSCAFT00845028599.1
    Conserved Domains (3) summary
    cd12029
    Location:163229
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:45123
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:319497
    Guanylate_kin; Guanylate kinase
  6. XM_038450222.1XP_038306150.1  disks large homolog 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C0PMV6
    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily
  7. XM_038450223.1XP_038306151.1  disks large homolog 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C0PMV6
    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily
  8. XM_038450224.1XP_038306152.1  disks large homolog 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C0PMV6
    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    53822238..53877672
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038523664.1XP_038379592.1  disks large homolog 3 isoform X2

    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:644822
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  2. XM_038523665.1XP_038379593.1  disks large homolog 3 isoform X3

    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:640818
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  3. XM_038523666.1XP_038379594.1  disks large homolog 3 isoform X4

    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:626804
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  4. XM_038523663.1XP_038379591.1  disks large homolog 3 isoform X1

    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:658836
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  5. XM_038523667.1XP_038379595.1  disks large homolog 3 isoform X5

    Conserved Domains (3) summary
    cd12029
    Location:163229
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:45123
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:319497
    Guanylate_kin; Guanylate kinase
  6. XM_038523668.1XP_038379596.1  disks large homolog 3 isoform X6

    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily
  7. XM_038523669.1XP_038379597.1  disks large homolog 3 isoform X6

    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily
  8. XM_038523670.1XP_038379598.1  disks large homolog 3 isoform X6

    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    55153323..55208774
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038652156.1XP_038508084.1  disks large homolog 3 isoform X2

    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:644822
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  2. XM_038652157.1XP_038508085.1  disks large homolog 3 isoform X3

    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:640818
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  3. XM_038652158.1XP_038508086.1  disks large homolog 3 isoform X4

    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:626804
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  4. XM_038652155.1XP_038508083.1  disks large homolog 3 isoform X1

    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:658836
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  5. XM_038652159.1XP_038508087.1  disks large homolog 3 isoform X5

    Conserved Domains (3) summary
    cd12029
    Location:163229
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:45123
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:319497
    Guanylate_kin; Guanylate kinase
  6. XM_038652160.1XP_038508088.1  disks large homolog 3 isoform X6

    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily
  7. XM_038652161.1XP_038508089.1  disks large homolog 3 isoform X6

    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily
  8. XM_038652162.1XP_038508090.1  disks large homolog 3 isoform X6

    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    55080264..55135709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038587633.1XP_038443561.1  disks large homolog 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L3X8
    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:644822
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  2. XM_038587634.1XP_038443562.1  disks large homolog 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L3X8
    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:640818
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  3. XM_038587635.1XP_038443563.1  disks large homolog 3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L3X8, A0A8C0TLW5, A0A8I3NVY0
    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:626804
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  4. XM_038587632.1XP_038443560.1  disks large homolog 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L3X8
    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:658836
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  5. XM_038587636.1XP_038443564.1  disks large homolog 3 isoform X5

    UniProtKB/TrEMBL
    A0A8C0L3K2, A0A8C0TP21, A0A8I3NW22
    Conserved Domains (3) summary
    cd12029
    Location:163229
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:45123
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:319497
    Guanylate_kin; Guanylate kinase
  6. XM_038587637.1XP_038443565.1  disks large homolog 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C0PMV6
    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily
  7. XM_038587638.1XP_038443566.1  disks large homolog 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C0PMV6
    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily
  8. XM_038587639.1XP_038443567.1  disks large homolog 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C0PMV6
    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    45713141..45768580
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005641450.4XP_005641507.2  disks large homolog 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L3X8
    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:644822
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  2. XM_038464710.1XP_038320638.1  disks large homolog 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L3X8
    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:640818
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  3. XM_038464711.1XP_038320639.1  disks large homolog 3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L3X8, A0A8C0TLW5, A0A8I3NVY0
    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:626804
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  4. XM_005641448.4XP_005641505.2  disks large homolog 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L3X8
    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:384462
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:658836
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:311385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:52130
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  5. XM_851654.6XP_856747.1  disks large homolog 3 isoform X5

    UniProtKB/TrEMBL
    A0A8C0L3K2, A0A8C0TP21, A0A8I3NW22
    Conserved Domains (3) summary
    cd12029
    Location:163229
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:45123
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:319497
    Guanylate_kin; Guanylate kinase
  6. XM_005641451.4XP_005641508.1  disks large homolog 3 isoform X6

    See identical proteins and their annotated locations for XP_005641508.1

    UniProtKB/TrEMBL
    A0A8C0PMV6
    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily
  7. XM_022415771.2XP_022271479.1  disks large homolog 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C0PMV6
    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily
  8. XM_038464712.1XP_038320640.1  disks large homolog 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C0PMV6
    Conserved Domains (2) summary
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:1985
    SH3; Src Homology 3 domain superfamily