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MSN moesin [ Canis lupus familiaris (dog) ]

Gene ID: 491924, updated on 17-Aug-2024

Summary

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Official Symbol
MSNprovided by VGNC
Official Full Name
moesinprovided by VGNC
Primary source
VGNC:VGNC:43447
See related
Ensembl:ENSCAFG00845027053
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See MSN in Genome Data Viewer
Location:
chromosome: X
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (51673014..51739539)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (41546746..41613249)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (50900835..50967356)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (49637614..49704123)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (50985533..51052067)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene natural cytotoxicity triggering receptor 3 ligand 1-like Neighboring gene ribosomal protein, large, P1 pseudogene Neighboring gene uncharacterized LOC119868451 Neighboring gene V-set and immunoglobulin domain containing 4 Neighboring gene microRNA mir-223 Neighboring gene signal peptidase complex subunit 1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. analysis of ezrin and moesin expression in canine and feline osteosarcoma
    Title: Ezrin and moesin expression in canine and feline osteosarcoma.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of early endosome to late endosome transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein localization to early endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of organelle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in apical part of cell IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in filopodium IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in microvillus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
moesin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    51673014..51739539
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038450167.1 → XP_038306095.1  moesin isoform X3

    UniProtKB/TrEMBL
    A0A8I3Q023, A0A8P0TCK5
    Conserved Domains (3) summary
    smart00295
    Location:1 → 195
    B41; Band 4.1 homologues
    cd13194
    Location:189 → 285
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:336 → 566
    ERM; Ezrin/radixin/moesin family

  2. XM_038450166.1 → XP_038306094.1  moesin isoform X2

    UniProtKB/TrEMBL
    A0A8C0KVN7, A0A8C0Z3D7, A0A8I3Q023, A0A8P0TCK5
    Conserved Domains (3) summary
    smart00295
    Location:7 → 206
    B41; Band 4.1 homologues
    cd13194
    Location:200 → 296
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:347 → 577
    ERM; Ezrin/radixin/moesin family

  3. XM_038450165.1 → XP_038306093.1  moesin isoform X1

    UniProtKB/TrEMBL
    A0A8C0NFX2, A0A8C0TCI6, A0A8I3PWU6
    Related
    ENSCAFP00845037623.1, ENSCAFT00845047957.1
    Conserved Domains (3) summary
    smart00295
    Location:22 → 221
    B41; Band 4.1 homologues
    cd13194
    Location:215 → 311
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:362 → 592
    ERM; Ezrin/radixin/moesin family

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    49637614..49704123
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038523611.1 → XP_038379539.1  moesin isoform X3

    Conserved Domains (3) summary
    smart00295
    Location:1 → 195
    B41; Band 4.1 homologues
    cd13194
    Location:189 → 285
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:336 → 566
    ERM; Ezrin/radixin/moesin family

  2. XM_038523610.1 → XP_038379538.1  moesin isoform X2

    Conserved Domains (3) summary
    smart00295
    Location:7 → 206
    B41; Band 4.1 homologues
    cd13194
    Location:200 → 296
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:347 → 577
    ERM; Ezrin/radixin/moesin family

  3. XM_038523609.1 → XP_038379537.1  moesin isoform X1

    Conserved Domains (3) summary
    smart00295
    Location:22 → 221
    B41; Band 4.1 homologues
    cd13194
    Location:215 → 311
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:362 → 592
    ERM; Ezrin/radixin/moesin family

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    50985533..51052067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038652107.1 → XP_038508035.1  moesin isoform X3

    Conserved Domains (3) summary
    smart00295
    Location:1 → 195
    B41; Band 4.1 homologues
    cd13194
    Location:189 → 285
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:336 → 566
    ERM; Ezrin/radixin/moesin family

  2. XM_038652106.1 → XP_038508034.1  moesin isoform X2

    Conserved Domains (3) summary
    smart00295
    Location:7 → 206
    B41; Band 4.1 homologues
    cd13194
    Location:200 → 296
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:347 → 577
    ERM; Ezrin/radixin/moesin family

  3. XM_038652105.1 → XP_038508033.1  moesin isoform X1

    Conserved Domains (3) summary
    smart00295
    Location:22 → 221
    B41; Band 4.1 homologues
    cd13194
    Location:215 → 311
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:362 → 592
    ERM; Ezrin/radixin/moesin family

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    50900835..50967356
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038587583.1 → XP_038443511.1  moesin isoform X3

    UniProtKB/TrEMBL
    A0A8I3Q023, A0A8P0TCK5
    Conserved Domains (3) summary
    smart00295
    Location:1 → 195
    B41; Band 4.1 homologues
    cd13194
    Location:189 → 285
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:336 → 566
    ERM; Ezrin/radixin/moesin family

  2. XM_038587582.1 → XP_038443510.1  moesin isoform X2

    UniProtKB/TrEMBL
    A0A8C0KVN7, A0A8C0Z3D7, A0A8I3Q023, A0A8P0TCK5
    Conserved Domains (3) summary
    smart00295
    Location:7 → 206
    B41; Band 4.1 homologues
    cd13194
    Location:200 → 296
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:347 → 577
    ERM; Ezrin/radixin/moesin family

  3. XM_038587581.1 → XP_038443509.1  moesin isoform X1

    UniProtKB/TrEMBL
    A0A8C0NFX2, A0A8C0TCI6, A0A8I3PWU6
    Conserved Domains (3) summary
    smart00295
    Location:22 → 221
    B41; Band 4.1 homologues
    cd13194
    Location:215 → 311
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:362 → 592
    ERM; Ezrin/radixin/moesin family

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    41546746..41613249
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014111741.3 → XP_013967216.1  moesin isoform X3

    UniProtKB/TrEMBL
    A0A8I3Q023, A0A8P0TCK5
    Conserved Domains (3) summary
    smart00295
    Location:1 → 195
    B41; Band 4.1 homologues
    cd13194
    Location:189 → 285
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:336 → 566
    ERM; Ezrin/radixin/moesin family

  2. XM_843243.6 → XP_848336.1  moesin isoform X2

    UniProtKB/TrEMBL
    A0A8C0KVN7, A0A8C0Z3D7, A0A8I3Q023, A0A8P0TCK5
    Conserved Domains (3) summary
    smart00295
    Location:7 → 206
    B41; Band 4.1 homologues
    cd13194
    Location:200 → 296
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:347 → 577
    ERM; Ezrin/radixin/moesin family

  3. XM_005641418.3 → XP_005641475.1  moesin isoform X1

    UniProtKB/TrEMBL
    A0A8C0NFX2, A0A8C0TCI6, A0A8I3PWU6
    Conserved Domains (3) summary
    smart00295
    Location:22 → 221
    B41; Band 4.1 homologues
    cd13194
    Location:215 → 311
    FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
    pfam00769
    Location:362 → 592
    ERM; Ezrin/radixin/moesin family
Nucleotide Protein
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