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ANKFN1 ankyrin repeat and fibronectin type III domain containing 1 [ Canis lupus familiaris (dog) ]

Gene ID: 491099, updated on 17-Aug-2024

Summary

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Official Symbol
ANKFN1provided by VGNC
Official Full Name
ankyrin repeat and fibronectin type III domain containing 1provided by VGNC
Primary source
VGNC:VGNC:37871
See related
Ensembl:ENSCAFG00845017522
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See ANKFN1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
21
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (31901572..32194395)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (30334298..30626943)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (31054421..31347435)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (30687635..30979993)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (30971338..31263802)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111097542 Neighboring gene ribosomal protein L37a pseudogene Neighboring gene cytochrome c oxidase subunit 6A1, mitochondrial-like Neighboring gene uncharacterized LOC119873302 Neighboring gene noggin Neighboring gene chromosome 9 C17orf67 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in establishment of mitotic spindle orientation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of establishment of bipolar cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in spindle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ankyrin repeat and fibronectin type-III domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    31901572..32194395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038677011.1 → XP_038532939.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3P101, A0A8I3P485
    Related
    ENSCAFP00845024523.1, ENSCAFT00845031324.1
    Conserved Domains (5) summary
    PHA03307
    Location:857 → 1090
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0666
    Location:57 → 217
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00063
    Location:271 → 364
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:137 → 171
    ANK; ANK repeat [structural motif]
    cl39094
    Location:141 → 216
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_038677010.1 → XP_038532938.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    COG0666
    Location:57 → 217
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00063
    Location:271 → 364
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:137 → 171
    ANK; ANK repeat [structural motif]
    cl39094
    Location:141 → 216
    Ank_2; Ankyrin repeats (3 copies)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    30687635..30979993
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038486024.1 → XP_038341952.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X2

    Conserved Domains (5) summary
    PHA03307
    Location:857 → 1090
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0666
    Location:57 → 217
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00063
    Location:271 → 364
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:137 → 171
    ANK; ANK repeat [structural motif]
    cl39094
    Location:141 → 216
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_038486023.1 → XP_038341951.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    COG0666
    Location:57 → 217
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00063
    Location:271 → 364
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:137 → 171
    ANK; ANK repeat [structural motif]
    cl39094
    Location:141 → 216
    Ank_2; Ankyrin repeats (3 copies)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    30971338..31263802
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038611787.1 → XP_038467715.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X2

    Conserved Domains (5) summary
    PHA03307
    Location:857 → 1090
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0666
    Location:57 → 217
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00063
    Location:271 → 364
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:137 → 171
    ANK; ANK repeat [structural motif]
    cl39094
    Location:141 → 216
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_038611786.1 → XP_038467714.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    COG0666
    Location:57 → 217
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00063
    Location:271 → 364
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:137 → 171
    ANK; ANK repeat [structural motif]
    cl39094
    Location:141 → 216
    Ank_2; Ankyrin repeats (3 copies)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    31054421..31347435
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038547805.1 → XP_038403733.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N4B0, A0A8C0RI30

  2. XM_038547804.1 → XP_038403732.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    COG0666
    Location:57 → 217
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00063
    Location:271 → 364
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:137 → 171
    ANK; ANK repeat [structural motif]
    cl39094
    Location:141 → 216
    Ank_2; Ankyrin repeats (3 copies)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    30334298..30626943
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038606909.1 → XP_038462837.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0TZ58, A0A8P0P7S3, A0A8P0SLD0
    Conserved Domains (5) summary
    PHA03307
    Location:857 → 1090
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0666
    Location:57 → 217
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00063
    Location:271 → 364
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:137 → 171
    ANK; ANK repeat [structural motif]
    cl39094
    Location:141 → 216
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_038606902.1 → XP_038462830.1  ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    COG0666
    Location:57 → 217
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00063
    Location:271 → 364
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    sd00045
    Location:137 → 171
    ANK; ANK repeat [structural motif]
    cl39094
    Location:141 → 216
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
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