U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TDP1 tyrosyl-DNA phosphodiesterase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 490828, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
TDP1provided by VGNC
Official Full Name
tyrosyl-DNA phosphodiesterase 1provided by VGNC
Primary source
VGNC:VGNC:47218
See related
Ensembl:ENSCAFG00845012856
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See TDP1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
21
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (61295027..61379934)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (60602950..60687315)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (61353607..61438500)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (60976795..61061437)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (61025579..61109935)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111097140 Neighboring gene EF-hand calcium binding domain 11 Neighboring gene uncharacterized LOC111097141 Neighboring gene small nucleolar RNA U13 Neighboring gene calcyclin-binding protein-like Neighboring gene potassium two pore domain channel subfamily K member 13

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-tyrosyl-DNA phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in single strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
tyrosyl-DNA phosphodiesterase 1
XP_005623796.1
XP_005623798.1
XP_013971600.1
XP_022278026.1
XP_022278027.1
XP_022278028.1
XP_022278029.1
XP_022278030.1
XP_038339968.1
XP_038339969.1
XP_038339970.1
XP_038339971.1
XP_038339972.1
XP_038339973.1
XP_038339974.1
XP_038339975.1
XP_038339976.1
XP_038339977.1
XP_038401463.1
XP_038401464.1
XP_038401465.1
XP_038401466.1
XP_038401467.1
XP_038401468.1
XP_038401469.1
XP_038401470.1
XP_038401471.1
XP_038401472.1
XP_038449727.1
XP_038465557.1
XP_038465558.1
XP_038465560.1
XP_038465561.1
XP_038465562.1
XP_038465563.1
XP_038465564.1
XP_038465565.1
XP_038465566.1
XP_038465567.1
XP_038530368.1
XP_038530369.1
XP_038530370.1
XP_038530371.1
XP_038530372.1
XP_038530373.1
XP_038530374.1
XP_038530375.1
XP_038530376.1
XP_038530377.1
XP_547950.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    61295027..61379934
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038674446.1 → XP_038530374.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  2. XM_038674440.1 → XP_038530368.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Related
    ENSCAFP00845017931.1, ENSCAFT00845022872.1
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  3. XM_038674448.1 → XP_038530376.1  tyrosyl-DNA phosphodiesterase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PVX1, A0A8C0R231, A0A8I3NK23
    Related
    ENSCAFP00845017976.1, ENSCAFT00845022933.1
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  4. XM_038674449.1 → XP_038530377.1  tyrosyl-DNA phosphodiesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3NQ61
    Related
    ENSCAFP00845018009.1, ENSCAFT00845022973.1
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 516
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  5. XM_038674447.1 → XP_038530375.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  6. XM_038674441.1 → XP_038530369.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  7. XM_038674443.1 → XP_038530371.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  8. XM_038674442.1 → XP_038530370.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  9. XM_038674444.1 → XP_038530372.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  10. XM_038674445.1 → XP_038530373.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    60976795..61061437
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038484046.1 → XP_038339974.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  2. XM_038484040.1 → XP_038339968.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  3. XM_038484048.1 → XP_038339976.1  tyrosyl-DNA phosphodiesterase 1 isoform X2

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  4. XM_038484049.1 → XP_038339977.1  tyrosyl-DNA phosphodiesterase 1 isoform X3

  5. XM_038484047.1 → XP_038339975.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  6. XM_038484041.1 → XP_038339969.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  7. XM_038484043.1 → XP_038339971.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  8. XM_038484042.1 → XP_038339970.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  9. XM_038484044.1 → XP_038339972.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  10. XM_038484045.1 → XP_038339973.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    61025579..61109935
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038609636.1 → XP_038465564.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  2. XM_038609629.1 → XP_038465557.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  3. XM_038609638.1 → XP_038465566.1  tyrosyl-DNA phosphodiesterase 1 isoform X2

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  4. XM_038609639.1 → XP_038465567.1  tyrosyl-DNA phosphodiesterase 1 isoform X3

  5. XM_038609637.1 → XP_038465565.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  6. XM_038609630.1 → XP_038465558.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  7. XM_038609633.1 → XP_038465561.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  8. XM_038609632.1 → XP_038465560.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  9. XM_038609634.1 → XP_038465562.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  10. XM_038609635.1 → XP_038465563.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    61353607..61438500
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038545541.1 → XP_038401469.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  2. XM_038545535.1 → XP_038401463.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  3. XM_038545543.1 → XP_038401471.1  tyrosyl-DNA phosphodiesterase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PVX1, A0A8C0R231, A0A8I3NK23
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  4. XM_038545544.1 → XP_038401472.1  tyrosyl-DNA phosphodiesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3NQ61
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 516
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  5. XM_038545542.1 → XP_038401470.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  6. XM_038545536.1 → XP_038401464.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  7. XM_038545538.1 → XP_038401466.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  8. XM_038545537.1 → XP_038401465.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  9. XM_038545539.1 → XP_038401467.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  10. XM_038545540.1 → XP_038401468.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    60602950..60687315
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038593799.1 → XP_038449727.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  2. XM_005623739.3 → XP_005623796.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    See identical proteins and their annotated locations for XP_005623796.1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  3. XM_547950.6 → XP_547950.2  tyrosyl-DNA phosphodiesterase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PVX1, A0A8C0R231, A0A8I3NK23
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  4. XM_022422322.2 → XP_022278030.1  tyrosyl-DNA phosphodiesterase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3NQ61
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 516
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  5. XM_022422321.2 → XP_022278029.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  6. XM_022422319.1 → XP_022278027.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  7. XM_022422320.2 → XP_022278028.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  8. XM_022422318.2 → XP_022278026.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  9. XM_005623741.3 → XP_005623798.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    See identical proteins and their annotated locations for XP_005623798.1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  10. XM_014116125.3 → XP_013971600.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVE6, A0A8C0PVZ0, A0A8I3NDZ4
    Conserved Domains (1) summary
    pfam06087
    Location:167 → 580
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.