U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

FRMD6 FERM domain containing 6 [ Canis lupus familiaris (dog) ]

Gene ID: 490688, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
FRMD6provided by VGNC
Official Full Name
FERM domain containing 6provided by VGNC
Primary source
VGNC:VGNC:40983
See related
Ensembl:ENSCAFG00845003527
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See FRMD6 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (27934649..28166956)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (27509615..27742043)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (28012258..28244423)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (27604816..27836513)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (27664576..27897009)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111097033 Neighboring gene uncharacterized LOC111097216 Neighboring gene thioredoxin related transmembrane protein 1 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC111097034 Neighboring gene G protein subunit gamma 2 Neighboring gene RNA transcription, translation and transport factor

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Report a willin(FRMD6)/Par3-aPKC-ROCK pathway that controls epithelial apical morphology.
    Title: Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in positive regulation of hippo signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
FERM domain-containing protein 6

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    27934649..28166956
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038673631.1 → XP_038529559.1  FERM domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RCM4, A0A8I3MPY8, A0A8P0TSZ4
    Conserved Domains (3) summary
    cd13185
    Location:227 → 335
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd14473
    Location:128 → 226
    FERM_B-lobe; FERM domain B-lobe
    cd17198
    Location:15 → 120
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

  2. XM_038673630.1 → XP_038529558.1  FERM domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RCM4, A0A8I3MPY8, A0A8P0TSZ4
    Related
    ENSCAFP00845005025.1, ENSCAFT00845006327.1
    Conserved Domains (3) summary
    cd13185
    Location:227 → 335
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd14473
    Location:128 → 226
    FERM_B-lobe; FERM domain B-lobe
    cd17198
    Location:15 → 120
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

  3. XM_038673632.1 → XP_038529560.1  FERM domain-containing protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MPX7, A0A8I3MPY8, A0A8P0NG58, A0A8P0TSZ4
    Related
    ENSCAFP00845004992.1, ENSCAFT00845006287.1
    Conserved Domains (3) summary
    smart00295
    Location:20 → 226
    B41; Band 4.1 homologues
    cd13185
    Location:219 → 327
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd17198
    Location:15 → 112
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    27604816..27836513
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038483259.1 → XP_038339187.1  FERM domain-containing protein 6 isoform X1

    Conserved Domains (3) summary
    cd13185
    Location:227 → 335
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd14473
    Location:128 → 226
    FERM_B-lobe; FERM domain B-lobe
    cd17198
    Location:15 → 120
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

  2. XM_038483257.1 → XP_038339185.1  FERM domain-containing protein 6 isoform X1

    Conserved Domains (3) summary
    cd13185
    Location:227 → 335
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd14473
    Location:128 → 226
    FERM_B-lobe; FERM domain B-lobe
    cd17198
    Location:15 → 120
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

  3. XM_038483260.1 → XP_038339188.1  FERM domain-containing protein 6 isoform X2

    Conserved Domains (3) summary
    smart00295
    Location:20 → 226
    B41; Band 4.1 homologues
    cd13185
    Location:219 → 327
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd17198
    Location:15 → 112
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    27664576..27897009
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038608829.1 → XP_038464757.1  FERM domain-containing protein 6 isoform X1

    Conserved Domains (3) summary
    cd13185
    Location:227 → 335
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd14473
    Location:128 → 226
    FERM_B-lobe; FERM domain B-lobe
    cd17198
    Location:15 → 120
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

  2. XM_038608828.1 → XP_038464756.1  FERM domain-containing protein 6 isoform X1

    Conserved Domains (3) summary
    cd13185
    Location:227 → 335
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd14473
    Location:128 → 226
    FERM_B-lobe; FERM domain B-lobe
    cd17198
    Location:15 → 120
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

  3. XM_038608830.1 → XP_038464758.1  FERM domain-containing protein 6 isoform X2

    Conserved Domains (3) summary
    smart00295
    Location:20 → 226
    B41; Band 4.1 homologues
    cd13185
    Location:219 → 327
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd17198
    Location:15 → 112
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    28012258..28244423
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038544706.1 → XP_038400634.1  FERM domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RCM4, A0A8I3MPY8, A0A8P0TSZ4
    Conserved Domains (3) summary
    cd13185
    Location:227 → 335
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd14473
    Location:128 → 226
    FERM_B-lobe; FERM domain B-lobe
    cd17198
    Location:15 → 120
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

  2. XM_038544705.1 → XP_038400633.1  FERM domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RCM4, A0A8I3MPY8, A0A8P0TSZ4
    Conserved Domains (3) summary
    cd13185
    Location:227 → 335
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd14473
    Location:128 → 226
    FERM_B-lobe; FERM domain B-lobe
    cd17198
    Location:15 → 120
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

  3. XM_038544707.1 → XP_038400635.1  FERM domain-containing protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MPX7, A0A8I3MPY8, A0A8P0NG58, A0A8P0TSZ4
    Conserved Domains (3) summary
    smart00295
    Location:20 → 226
    B41; Band 4.1 homologues
    cd13185
    Location:219 → 327
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd17198
    Location:15 → 112
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    27509615..27742043
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022422002.2 → XP_022277710.1  FERM domain-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0RCM4, A0A8I3MPY8, A0A8P0TSZ4
    Conserved Domains (3) summary
    cd13185
    Location:227 → 335
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd14473
    Location:128 → 226
    FERM_B-lobe; FERM domain B-lobe
    cd17198
    Location:15 → 120
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

  2. XM_005623395.4 → XP_005623452.1  FERM domain-containing protein 6 isoform X1

    See identical proteins and their annotated locations for XP_005623452.1

    UniProtKB/TrEMBL
    A0A8C0RCM4, A0A8I3MPY8, A0A8P0TSZ4
    Conserved Domains (3) summary
    cd13185
    Location:227 → 335
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd14473
    Location:128 → 226
    FERM_B-lobe; FERM domain B-lobe
    cd17198
    Location:15 → 120
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

  3. XM_858957.6 → XP_864050.1  FERM domain-containing protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MPX7, A0A8I3MPY8, A0A8P0NG58, A0A8P0TSZ4
    Conserved Domains (3) summary
    smart00295
    Location:20 → 226
    B41; Band 4.1 homologues
    cd13185
    Location:219 → 327
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    cd17198
    Location:15 → 112
    FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials