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LOC490356 lymphotactin [ Canis lupus familiaris (dog) ]

Gene ID: 490356, updated on 22-Jan-2024

Summary

Gene symbol
LOC490356
Gene description
lymphotactin
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
XCL1; XCL2
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Genomic context

See LOC490356 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (29804708..29995081, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (29518512..29708129, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (29911837..30102031, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (29637969..29827991, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (29673524..29863628, complement)

Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111096671 Neighboring gene uncharacterized LOC102152546 Neighboring gene 40S ribosomal protein S2-like Neighboring gene uncharacterized LOC102152661 Neighboring gene uncharacterized LOC119872530 Neighboring gene uncharacterized LOC111096672 Neighboring gene U2 spliceosomal RNA Neighboring gene T-box transcription factor 19 Neighboring gene SFT2 domain containing 2

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CCR chemokine receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables chemokine activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to interleukin-1 IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to tumor necrosis factor IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to type II interferon IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in chemokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in lymphocyte chemotaxis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in monocyte chemotaxis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in neutrophil chemotaxis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of T cell chemotaxis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
cytokine SCM-1 beta; lymphotactin; uncharacterized protein LOC490356
Names
X-C motif chemokine ligand 2
chemokine (C motif) ligand 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051811.1 Reference ROS_Cfam_1.0

    Range
    29804708..29995081 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038671436.1XP_038527364.1  lymphotactin isoform X3

    UniProtKB/TrEMBL
    A0A8P0PL06
    Conserved Domains (1) summary
    cd00271
    Location:109178
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  2. XM_038671435.1XP_038527363.1  lymphotactin isoform X2

    Conserved Domains (1) summary
    cd00271
    Location:123192
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  3. XM_038671438.1XP_038527366.1  lymphotactin isoform X5

    UniProtKB/TrEMBL
    A0A8P0PL06
    Conserved Domains (1) summary
    cd00271
    Location:88157
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  4. XM_038671439.1XP_038527367.1  lymphotactin isoform X1

    UniProtKB/TrEMBL
    A0A8C0LF89, A0A8C0PT44
    Conserved Domains (1) summary
    cd00271
    Location:34103
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  5. XM_038671437.1XP_038527365.1  lymphotactin isoform X4

    UniProtKB/TrEMBL
    A0A8P0PL06
    Conserved Domains (1) summary
    cd00271
    Location:105174
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049267.1 Alternate UMICH_Zoey_3.1

    Range
    29637969..29827991 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038481255.1XP_038337183.1  lymphotactin isoform X1

    Conserved Domains (1) summary
    cd00271
    Location:34103
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  2. XM_038481252.1XP_038337180.1  uncharacterized protein LOC490356 isoform X6

  3. XM_038481254.1XP_038337182.1  lymphotactin isoform X8

    Conserved Domains (1) summary
    cd00271
    Location:78147
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  4. XM_038481253.1XP_038337181.1  lymphotactin isoform X7

    Conserved Domains (1) summary
    cd00271
    Location:105174
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

    Range
    29673524..29863628 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038606766.1XP_038462694.1  lymphotactin isoform X1

    Conserved Domains (1) summary
    cd00271
    Location:34103
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  2. XM_038606763.1XP_038462691.1  uncharacterized protein LOC490356 isoform X9

  3. XM_038606765.1XP_038462693.1  lymphotactin isoform X11

    Conserved Domains (1) summary
    cd00271
    Location:88157
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  4. XM_038606764.1XP_038462692.1  lymphotactin isoform X10

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

    Range
    29911837..30102031 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038542611.1XP_038398539.1  lymphotactin isoform X1

    UniProtKB/TrEMBL
    A0A8C0LF89, A0A8C0PT44
    Conserved Domains (1) summary
    cd00271
    Location:34103
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  2. XM_038542608.1XP_038398536.1  uncharacterized protein LOC490356 isoform X12

  3. XM_038542610.1XP_038398538.1  lymphotactin isoform X14

    UniProtKB/TrEMBL
    A0A8P0PL06
    Conserved Domains (1) summary
    cd00271
    Location:88157
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  4. XM_038542609.1XP_038398537.1  lymphotactin isoform X13

    UniProtKB/TrEMBL
    A0A8P0PL06
    Conserved Domains (1) summary
    cd00271
    Location:105174
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    29518512..29708129 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022421696.2XP_022277404.2  lymphotactin isoform X16

    UniProtKB/TrEMBL
    A0A8P0PL06
    Conserved Domains (1) summary
    cd00271
    Location:109178
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  2. XM_038567326.1XP_038423254.1  lymphotactin isoform X15

    UniProtKB/TrEMBL
    A0A8P0NNF9
    Conserved Domains (1) summary
    cd00271
    Location:123192
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  3. XM_038567351.1XP_038423279.1  lymphotactin isoform X18

    UniProtKB/TrEMBL
    A0A8P0PL06
    Conserved Domains (1) summary
    cd00271
    Location:88157
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...
  4. XM_038567343.1XP_038423271.1  lymphotactin isoform X17

    UniProtKB/TrEMBL
    A0A8P0PL06
    Conserved Domains (1) summary
    cd00271
    Location:105174
    Chemokine_C; C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) subclass. The two ...