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TNIK TRAF2 and NCK interacting kinase [ Canis lupus familiaris (dog) ]

Gene ID: 488166, updated on 17-Aug-2024

Summary

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Official Symbol
TNIKprovided by VGNC
Official Full Name
TRAF2 and NCK interacting kinaseprovided by VGNC
Primary source
VGNC:VGNC:47675
See related
Ensembl:ENSCAFG00845023590
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See TNIK in Genome Data Viewer
Location:
chromosome: 34
Exon count:
35
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 34 NC_051838.1 (35509666..35891390, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 34 NC_006616.4 (44437640..44820028, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 34 NC_049255.1 (35680818..36057283, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 34 NC_049294.1 (35448700..35832182, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 34 NC_049775.1 (35418689..35795208, complement)

Chromosome 34 - NC_051838.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867530 Neighboring gene uncharacterized LOC119867531 Neighboring gene zinc finger CCHC domain-containing protein 9-like Neighboring gene uncharacterized LOC111093943 Neighboring gene phospholipase D1 Neighboring gene transmembrane protein 212

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: TRAF2 and NCK-interacting protein kinase; TRAF2 and NCK-interacting protein kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051838.1 Reference ROS_Cfam_1.0

    Range
    35509666..35891390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038446070.1 → XP_038301998.1  TRAF2 and NCK-interacting protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8C0YX54, A0A8I3PQQ5, A0A8P0T2I2
    Related
    ENSCAFP00845033395.1, ENSCAFT00845042596.1
    Conserved Domains (2) summary
    smart00036
    Location:1042 → 1340
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  2. XM_038446067.1 → XP_038301995.1  TRAF2 and NCK-interacting protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0PMI3, A0A8C0SES9, A0A8I3PFQ4
    Related
    ENSCAFP00845032827.1, ENSCAFT00845041849.1
    Conserved Domains (2) summary
    smart00036
    Location:1071 → 1369
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  3. XM_038446072.1 → XP_038302000.1  TRAF2 and NCK-interacting protein kinase isoform X6

    UniProtKB/TrEMBL
    A0A8C0YX54
    Conserved Domains (2) summary
    smart00036
    Location:1013 → 1311
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  4. XM_038446068.1 → XP_038301996.1  TRAF2 and NCK-interacting protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8C0SER7, A0A8I3PFN5, A0A8P0T5F1
    Related
    ENSCAFP00845033026.1, ENSCAFT00845042108.1
    Conserved Domains (2) summary
    smart00036
    Location:1063 → 1361
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  5. XM_038446069.1 → XP_038301997.1  TRAF2 and NCK-interacting protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8C0SES9, A0A8I3PZG4, A0A8P0T1F8
    Related
    ENSCAFP00845033184.1, ENSCAFT00845042329.1
    Conserved Domains (2) summary
    smart00036
    Location:1042 → 1340
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  6. XM_038446073.1 → XP_038302001.1  TRAF2 and NCK-interacting protein kinase isoform X7

    UniProtKB/TrEMBL
    A0A8C0YX54
    Conserved Domains (2) summary
    smart00036
    Location:1005 → 1303
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  7. XM_038446071.1 → XP_038301999.1  TRAF2 and NCK-interacting protein kinase isoform X5

    UniProtKB/TrEMBL
    A0A8C0SER7
    Conserved Domains (2) summary
    smart00036
    Location:1034 → 1332
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  8. XM_038446074.1 → XP_038302002.1  TRAF2 and NCK-interacting protein kinase isoform X8

    UniProtKB/TrEMBL
    A0A8I3PRG8, A0A8P0NGW6
    Related
    ENSCAFP00845033833.1, ENSCAFT00845043152.1
    Conserved Domains (2) summary
    smart00036
    Location:1000 → 1298
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cl21453
    Location:1 → 242
    PKc_like; Protein Kinases, catalytic domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049294.1 Alternate UMICH_Zoey_3.1

    Range
    35448700..35832182 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038520258.1 → XP_038376186.1  LOW QUALITY PROTEIN: TRAF2 and NCK-interacting protein kinase isoform X3

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049775.1 Alternate UNSW_CanFamBas_1.0

    Range
    35418689..35795208 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038648303.1 → XP_038504231.1  TRAF2 and NCK-interacting protein kinase isoform X1

    Conserved Domains (2) summary
    smart00036
    Location:1071 → 1369
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  2. XM_038648306.1 → XP_038504234.1  TRAF2 and NCK-interacting protein kinase isoform X4

    Conserved Domains (2) summary
    smart00036
    Location:1042 → 1340
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  3. XM_038648304.1 → XP_038504232.1  TRAF2 and NCK-interacting protein kinase isoform X2

    Conserved Domains (2) summary
    smart00036
    Location:1063 → 1361
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  4. XM_038648305.1 → XP_038504233.1  TRAF2 and NCK-interacting protein kinase isoform X3

    Conserved Domains (2) summary
    smart00036
    Location:1042 → 1340
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  5. XM_038648309.1 → XP_038504237.1  TRAF2 and NCK-interacting protein kinase isoform X7

    Conserved Domains (2) summary
    smart00036
    Location:1005 → 1303
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  6. XM_038648308.1 → XP_038504236.1  TRAF2 and NCK-interacting protein kinase isoform X6

    Conserved Domains (2) summary
    smart00036
    Location:1013 → 1311
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  7. XM_038648307.1 → XP_038504235.1  TRAF2 and NCK-interacting protein kinase isoform X5

    Conserved Domains (2) summary
    smart00036
    Location:1034 → 1332
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  8. XM_038648310.1 → XP_038504238.1  TRAF2 and NCK-interacting protein kinase isoform X8

    Conserved Domains (2) summary
    smart00036
    Location:1000 → 1298
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cl21453
    Location:1 → 242
    PKc_like; Protein Kinases, catalytic domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049255.1 Alternate UU_Cfam_GSD_1.0

    Range
    35680818..36057283 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038583888.1 → XP_038439816.1  TRAF2 and NCK-interacting protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0PMI3, A0A8C0SES9, A0A8I3PFQ4
    Conserved Domains (2) summary
    smart00036
    Location:1071 → 1369
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  2. XM_038583893.1 → XP_038439821.1  TRAF2 and NCK-interacting protein kinase isoform X6

    UniProtKB/TrEMBL
    A0A8C0YX54
    Conserved Domains (2) summary
    smart00036
    Location:1013 → 1311
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  3. XM_038583891.1 → XP_038439819.1  TRAF2 and NCK-interacting protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8C0YX54, A0A8I3PQQ5, A0A8P0T2I2
    Conserved Domains (2) summary
    smart00036
    Location:1042 → 1340
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  4. XM_038583889.1 → XP_038439817.1  TRAF2 and NCK-interacting protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8C0SER7, A0A8I3PFN5, A0A8P0T5F1
    Conserved Domains (2) summary
    smart00036
    Location:1063 → 1361
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  5. XM_038583890.1 → XP_038439818.1  TRAF2 and NCK-interacting protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8C0SES9, A0A8I3PZG4, A0A8P0T1F8
    Conserved Domains (2) summary
    smart00036
    Location:1042 → 1340
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  6. XM_038583894.1 → XP_038439822.1  TRAF2 and NCK-interacting protein kinase isoform X7

    UniProtKB/TrEMBL
    A0A8C0YX54
    Conserved Domains (2) summary
    smart00036
    Location:1005 → 1303
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  7. XM_038583892.1 → XP_038439820.1  TRAF2 and NCK-interacting protein kinase isoform X5

    UniProtKB/TrEMBL
    A0A8C0SER7
    Conserved Domains (2) summary
    smart00036
    Location:1034 → 1332
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  8. XM_038583895.1 → XP_038439823.1  TRAF2 and NCK-interacting protein kinase isoform X8

    UniProtKB/TrEMBL
    A0A8I3PRG8, A0A8P0NGW6
    Conserved Domains (2) summary
    smart00036
    Location:1000 → 1298
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cl21453
    Location:1 → 242
    PKc_like; Protein Kinases, catalytic domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006616.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    44437640..44820028 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038462813.1 → XP_038318741.1  TRAF2 and NCK-interacting protein kinase isoform X4

    UniProtKB/TrEMBL
    A0A8C0YX54, A0A8I3PQQ5, A0A8P0T2I2
    Conserved Domains (2) summary
    smart00036
    Location:1042 → 1340
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  2. XM_038462810.1 → XP_038318738.1  TRAF2 and NCK-interacting protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0PMI3, A0A8C0SES9, A0A8I3PFQ4
    Conserved Domains (2) summary
    smart00036
    Location:1071 → 1369
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  3. XM_038462816.1 → XP_038318744.1  TRAF2 and NCK-interacting protein kinase isoform X6

    UniProtKB/TrEMBL
    A0A8C0YX54
    Conserved Domains (2) summary
    smart00036
    Location:1013 → 1311
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  4. XM_038462811.1 → XP_038318739.1  TRAF2 and NCK-interacting protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8C0SER7, A0A8I3PFN5, A0A8P0T5F1
    Conserved Domains (2) summary
    smart00036
    Location:1063 → 1361
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  5. XM_038462812.1 → XP_038318740.1  TRAF2 and NCK-interacting protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8C0SES9, A0A8I3PZG4, A0A8P0T1F8
    Conserved Domains (2) summary
    smart00036
    Location:1042 → 1340
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  6. XM_038462817.1 → XP_038318745.1  TRAF2 and NCK-interacting protein kinase isoform X7

    UniProtKB/TrEMBL
    A0A8C0YX54
    Conserved Domains (2) summary
    smart00036
    Location:1005 → 1303
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  7. XM_038462814.1 → XP_038318742.1  TRAF2 and NCK-interacting protein kinase isoform X5

    UniProtKB/TrEMBL
    A0A8C0SER7
    Conserved Domains (2) summary
    smart00036
    Location:1034 → 1332
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06637
    Location:18 → 313
    STKc_TNIK; Catalytic domain of the Serine/Threonine Kinase, Traf2- and Nck-Interacting Kinase

  8. XM_022414124.2 → XP_022269832.1  TRAF2 and NCK-interacting protein kinase isoform X8

    UniProtKB/TrEMBL
    A0A8I3PRG8, A0A8P0NGW6
    Conserved Domains (2) summary
    smart00036
    Location:1000 → 1298
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cl21453
    Location:1 → 242
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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