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VPS18 VPS18 core subunit of CORVET and HOPS complexes [ Canis lupus familiaris (dog) ]

Gene ID: 487503, updated on 17-Aug-2024

Summary

Official Symbol
VPS18provided by VGNC
Official Full Name
VPS18 core subunit of CORVET and HOPS complexesprovided by VGNC
Primary source
VGNC:VGNC:48279
See related
Ensembl:ENSCAFG00845029092
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See VPS18 in Genome Data Viewer
Location:
chromosome: 30
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (8156484..8165382)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (8082485..8091381)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (8317470..8326365)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (8079695..8088582)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (8186066..8194955)

Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene serine peptidase inhibitor, Kunitz type 1 Neighboring gene ras homolog family member V Neighboring gene uncharacterized LOC111093309 Neighboring gene delta like canonical Notch ligand 4 Neighboring gene ChaC glutathione specific gamma-glutamylcyclotransferase 1

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein-macromolecule adaptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in endosome organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in endosome to lysosome transport IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in lysosome organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in organelle fusion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in vesicle docking involved in exocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of HOPS complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
vacuolar protein sorting-associated protein 18 homolog; LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 18 homolog
Names
VPS18, CORVET/HOPS core subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051834.1 Reference ROS_Cfam_1.0

    Range
    8156484..8165382
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038442006.1XP_038297934.1  vacuolar protein sorting-associated protein 18 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0JW33, A0A8C0P7C4, A0A8C0TZ71, A0A8I3Q5H4
    Related
    ENSCAFP00845040407.1, ENSCAFT00845051495.1
    Conserved Domains (3) summary
    cd16689
    Location:851881
    RING-H2_Vps18; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 18 (Vps18) and similar proteins
    pfam00637
    Location:615743
    Clathrin; Region in Clathrin and VPS
    pfam05131
    Location:291434
    Pep3_Vps18; Pep3/Vps18/deep orange family
  2. XM_038442007.1XP_038297935.1  vacuolar protein sorting-associated protein 18 homolog isoform X2

    UniProtKB/TrEMBL
    A0A8C0TZ71
    Related
    ENSCAFP00845040377.1, ENSCAFT00845051463.1
    Conserved Domains (3) summary
    cd16689
    Location:783813
    RING-H2_Vps18; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 18 (Vps18) and similar proteins
    pfam00637
    Location:547675
    Clathrin; Region in Clathrin and VPS
    pfam05131
    Location:223366
    Pep3_Vps18; Pep3/Vps18/deep orange family

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049290.1 Alternate UMICH_Zoey_3.1

    Range
    8079695..8088582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038516496.1XP_038372424.1  LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 18 homolog isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

    Range
    8186066..8194955
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038644369.1XP_038500297.1  vacuolar protein sorting-associated protein 18 homolog isoform X1

  2. XM_038644370.1XP_038500298.1  vacuolar protein sorting-associated protein 18 homolog isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

    Range
    8317470..8326365
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038580087.1XP_038436015.1  vacuolar protein sorting-associated protein 18 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0JW33, A0A8C0P7C4, A0A8C0TZ71, A0A8I3Q5H4
    Conserved Domains (3) summary
    cd16689
    Location:851881
    RING-H2_Vps18; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 18 (Vps18) and similar proteins
    pfam00637
    Location:615743
    Clathrin; Region in Clathrin and VPS
    pfam05131
    Location:291434
    Pep3_Vps18; Pep3/Vps18/deep orange family
  2. XM_038580088.1XP_038436016.1  vacuolar protein sorting-associated protein 18 homolog isoform X2

    UniProtKB/TrEMBL
    A0A8C0TZ71
    Conserved Domains (3) summary
    cd16689
    Location:783813
    RING-H2_Vps18; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 18 (Vps18) and similar proteins
    pfam00637
    Location:547675
    Clathrin; Region in Clathrin and VPS
    pfam05131
    Location:223366
    Pep3_Vps18; Pep3/Vps18/deep orange family

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    8082485..8091381
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_544627.7XP_544627.3  vacuolar protein sorting-associated protein 18 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8C0JW33, A0A8C0P7C4, A0A8C0TZ71, A0A8I3Q5H4
    Conserved Domains (3) summary
    cd16689
    Location:851881
    RING-H2_Vps18; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 18 (Vps18) and similar proteins
    pfam00637
    Location:615743
    Clathrin; Region in Clathrin and VPS
    pfam05131
    Location:291434
    Pep3_Vps18; Pep3/Vps18/deep orange family
  2. XM_022412692.2XP_022268400.1  vacuolar protein sorting-associated protein 18 homolog isoform X2

    UniProtKB/TrEMBL
    A0A8C0TZ71
    Conserved Domains (3) summary
    cd16689
    Location:783813
    RING-H2_Vps18; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 18 (Vps18) and similar proteins
    pfam00637
    Location:547675
    Clathrin; Region in Clathrin and VPS
    pfam05131
    Location:223366
    Pep3_Vps18; Pep3/Vps18/deep orange family