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ARHGAP12 Rho GTPase activating protein 12 [ Canis lupus familiaris (dog) ]

Gene ID: 487088, updated on 17-Aug-2024

Summary

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Official Symbol
ARHGAP12provided by VGNC
Official Full Name
Rho GTPase activating protein 12provided by VGNC
Primary source
VGNC:VGNC:38046
See related
Ensembl:ENSCAFG00845010136
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See ARHGAP12 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
27
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (13195757..13350836)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (12447199..12602262)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (12800653..12955754)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (12635843..12790873)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (12527046..12681618)

Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene phosphate carrier protein, mitochondrial-like Neighboring gene kinesin family member 5B Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC111091363 Neighboring gene uncharacterized LOC111091364 Neighboring gene uncharacterized LOC106560015 Neighboring gene uncharacterized LOC119881405

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051806.1 Reference ROS_Cfam_1.0

    Range
    13195757..13350836
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038658195.1 → XP_038514123.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  2. XM_038658207.1 → XP_038514135.1  rho GTPase-activating protein 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  3. XM_038658198.1 → XP_038514126.1  rho GTPase-activating protein 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Related
    ENSCAFP00845013993.1, ENSCAFT00845017964.1
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  4. XM_038658206.1 → XP_038514134.1  rho GTPase-activating protein 12 isoform X10

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 808
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  5. XM_038658204.1 → XP_038514132.1  rho GTPase-activating protein 12 isoform X8

    UniProtKB/TrEMBL
    A0A8I3NDX4, A0A8P0S9P8
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  6. XM_038658194.1 → XP_038514122.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  7. XM_038658199.1 → XP_038514127.1  rho GTPase-activating protein 12 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PK53, A0A8I3N9U9
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:432 → 543
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:621 → 790
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  8. XM_038658201.1 → XP_038514129.1  rho GTPase-activating protein 12 isoform X6

    UniProtKB/TrEMBL
    A0A8C0R8E2
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 362
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:410 → 521
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:599 → 768
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  9. XM_038658200.1 → XP_038514128.1  rho GTPase-activating protein 12 isoform X5

    UniProtKB/TrEMBL
    A0A8I3NDX4, A0A8P0S9P8
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  10. XM_038658205.1 → XP_038514133.1  rho GTPase-activating protein 12 isoform X9

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 823
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  11. XM_038658208.1 → XP_038514136.1  rho GTPase-activating protein 12 isoform X11

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  12. XM_038658202.1 → XP_038514130.1  rho GTPase-activating protein 12 isoform X7

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Related
    ENSCAFP00845014077.1, ENSCAFT00845018070.1
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:646 → 831
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  13. XM_038658196.1 → XP_038514124.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  14. XM_038658197.1 → XP_038514125.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  15. XM_038658209.1 → XP_038514137.1  rho GTPase-activating protein 12 isoform X12

    UniProtKB/TrEMBL
    A0A8C0PK53, A0A8I3N9U9
    Related
    ENSCAFP00845013939.1, ENSCAFT00845017894.1
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:621 → 806
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:432 → 543
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

RNA

  1. XR_005422791.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049262.1 Alternate UMICH_Zoey_3.1

    Range
    12635843..12790873
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038469165.1 → XP_038325093.1  rho GTPase-activating protein 12 isoform X2

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  2. XM_038469177.1 → XP_038325105.1  rho GTPase-activating protein 12 isoform X1

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  3. XM_038469168.1 → XP_038325096.1  rho GTPase-activating protein 12 isoform X3

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  4. XM_038469176.1 → XP_038325104.1  rho GTPase-activating protein 12 isoform X10

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 808
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  5. XM_038469174.1 → XP_038325102.1  rho GTPase-activating protein 12 isoform X8

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  6. XM_038469164.1 → XP_038325092.1  rho GTPase-activating protein 12 isoform X2

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  7. XM_038469169.1 → XP_038325097.1  rho GTPase-activating protein 12 isoform X4

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:432 → 543
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:621 → 790
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  8. XM_038469171.1 → XP_038325099.1  rho GTPase-activating protein 12 isoform X6

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 362
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:410 → 521
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:599 → 768
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  9. XM_038469170.1 → XP_038325098.1  rho GTPase-activating protein 12 isoform X5

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  10. XM_038469175.1 → XP_038325103.1  rho GTPase-activating protein 12 isoform X9

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 823
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  11. XM_038469178.1 → XP_038325106.1  rho GTPase-activating protein 12 isoform X11

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  12. XM_038469172.1 → XP_038325100.1  rho GTPase-activating protein 12 isoform X7

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:646 → 831
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  13. XM_038469166.1 → XP_038325094.1  rho GTPase-activating protein 12 isoform X2

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  14. XM_038469167.1 → XP_038325095.1  rho GTPase-activating protein 12 isoform X2

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  15. XM_038469179.1 → XP_038325107.1  rho GTPase-activating protein 12 isoform X12

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:621 → 806
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:432 → 543
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

RNA

  1. XR_005321597.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

    Range
    12527046..12681618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038594127.1 → XP_038450055.1  rho GTPase-activating protein 12 isoform X2

  2. XM_038594134.1 → XP_038450062.1  rho GTPase-activating protein 12 isoform X13

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  3. XM_038594130.1 → XP_038450058.1  rho GTPase-activating protein 12 isoform X3

  4. XM_038594139.1 → XP_038450067.1  rho GTPase-activating protein 12 isoform X10

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 808
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  5. XM_038594137.1 → XP_038450065.1  rho GTPase-activating protein 12 isoform X8

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  6. XM_038594131.1 → XP_038450059.1  rho GTPase-activating protein 12 isoform X4

  7. XM_038594126.1 → XP_038450054.1  rho GTPase-activating protein 12 isoform X2

  8. XM_038594135.1 → XP_038450063.1  rho GTPase-activating protein 12 isoform X6

  9. XM_038594133.1 → XP_038450061.1  rho GTPase-activating protein 12 isoform X5

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  10. XM_038594138.1 → XP_038450066.1  rho GTPase-activating protein 12 isoform X9

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 823
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  11. XM_038594140.1 → XP_038450068.1  rho GTPase-activating protein 12 isoform X11

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  12. XM_038594136.1 → XP_038450064.1  rho GTPase-activating protein 12 isoform X7

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:646 → 831
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  13. XM_038594128.1 → XP_038450056.1  rho GTPase-activating protein 12 isoform X2

  14. XM_038594129.1 → XP_038450057.1  rho GTPase-activating protein 12 isoform X2

  15. XM_038594141.1 → XP_038450069.1  rho GTPase-activating protein 12 isoform X12

    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:621 → 806
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:432 → 543
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

RNA

  1. XR_005389770.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

    Range
    12800653..12955754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038529875.1 → XP_038385803.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  2. XM_038529886.1 → XP_038385814.1  rho GTPase-activating protein 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  3. XM_038529878.1 → XP_038385806.1  rho GTPase-activating protein 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  4. XM_038529885.1 → XP_038385813.1  rho GTPase-activating protein 12 isoform X10

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 808
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  5. XM_038529883.1 → XP_038385811.1  rho GTPase-activating protein 12 isoform X8

    UniProtKB/TrEMBL
    A0A8I3NDX4, A0A8P0S9P8
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  6. XM_038529874.1 → XP_038385802.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  7. XM_038529879.1 → XP_038385807.1  rho GTPase-activating protein 12 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PK53, A0A8I3N9U9
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:432 → 543
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:621 → 790
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  8. XM_038529881.1 → XP_038385809.1  rho GTPase-activating protein 12 isoform X6

    UniProtKB/TrEMBL
    A0A8C0R8E2
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 362
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:410 → 521
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:599 → 768
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  9. XM_038529880.1 → XP_038385808.1  rho GTPase-activating protein 12 isoform X5

    UniProtKB/TrEMBL
    A0A8I3NDX4, A0A8P0S9P8
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  10. XM_038529884.1 → XP_038385812.1  rho GTPase-activating protein 12 isoform X9

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 823
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  11. XM_038529887.1 → XP_038385815.1  rho GTPase-activating protein 12 isoform X11

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  12. XM_038529882.1 → XP_038385810.1  rho GTPase-activating protein 12 isoform X7

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:646 → 831
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  13. XM_038529876.1 → XP_038385804.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  14. XM_038529877.1 → XP_038385805.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  15. XM_038529888.1 → XP_038385816.1  rho GTPase-activating protein 12 isoform X12

    UniProtKB/TrEMBL
    A0A8C0PK53, A0A8I3N9U9
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:621 → 806
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:432 → 543
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

RNA

  1. XR_005355203.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    12447199..12602262
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022406887.2 → XP_022262595.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  2. XM_014121961.3 → XP_013977436.2  rho GTPase-activating protein 12 isoform X14

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  3. XM_022406895.2 → XP_022262603.1  rho GTPase-activating protein 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  4. XM_022406930.2 → XP_022262638.1  rho GTPase-activating protein 12 isoform X10

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 808
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  5. XM_005617034.4 → XP_005617091.1  rho GTPase-activating protein 12 isoform X8

    UniProtKB/TrEMBL
    A0A8I3NDX4, A0A8P0S9P8
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  6. XM_022406884.2 → XP_022262592.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  7. XM_022406900.2 → XP_022262608.1  rho GTPase-activating protein 12 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PK53, A0A8I3N9U9
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:432 → 543
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:621 → 790
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  8. XM_022406913.2 → XP_022262621.1  rho GTPase-activating protein 12 isoform X6

    UniProtKB/TrEMBL
    A0A8C0R8E2
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 362
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:410 → 521
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:599 → 768
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  9. XM_022406904.2 → XP_022262612.1  rho GTPase-activating protein 12 isoform X5

    UniProtKB/TrEMBL
    A0A8I3NDX4, A0A8P0S9P8
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  10. XM_022406928.2 → XP_022262636.1  rho GTPase-activating protein 12 isoform X9

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 823
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  11. XM_038456370.1 → XP_038312298.1  rho GTPase-activating protein 12 isoform X11

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 781
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  12. XM_854654.6 → XP_859747.1  rho GTPase-activating protein 12 isoform X7

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:646 → 831
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

  13. XM_022406890.2 → XP_022262598.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  14. XM_022406893.2 → XP_022262601.1  rho GTPase-activating protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPE7, A0A8I3NQR4
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd13233
    Location:457 → 568
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
    cl02570
    Location:646 → 815
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  15. XM_014121964.3 → XP_013977439.1  rho GTPase-activating protein 12 isoform X12

    UniProtKB/TrEMBL
    A0A8C0PK53, A0A8I3N9U9
    Conserved Domains (6) summary
    cd12070
    Location:13 → 72
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:256 → 409
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:265 → 295
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:621 → 806
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:432 → 543
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
    pfam16618
    Location:69 → 263
    SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12

RNA

  1. XR_005313102.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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