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SOX17 SRY-box transcription factor 17 [ Canis lupus familiaris (dog) ]

Gene ID: 486955, updated on 17-Aug-2024

Summary

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Official Symbol
SOX17provided by VGNC
Official Full Name
SRY-box transcription factor 17provided by VGNC
Primary source
VGNC:VGNC:46676
See related
Ensembl:ENSCAFG00845026119
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See SOX17 in Genome Data Viewer
Location:
chromosome: 29
Exon count:
2
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 29 NC_051833.1 (6057575..6059968)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 29 NC_006611.4 (6289199..6291617)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 29 NC_049250.1 (6377256..6379697)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 29 NC_049289.1 (5992409..5994803)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 29 NC_049770.1 (6198380..6200809)

Chromosome 29 - NC_051833.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene mitochondrial ribosomal protein L15 Neighboring gene uncharacterized LOC119866698 Neighboring gene lipoxygenase homology domain-containing protein 1-like Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene RP1 axonemal microtubule associated

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anatomical structure morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vasculogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor SOX-17; LOW QUALITY PROTEIN: transcription factor SOX-17
Names
SRY-box 17

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051833.1 Reference ROS_Cfam_1.0

    Range
    6057575..6059968
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038441118.1 → XP_038297046.1  transcription factor SOX-17

    UniProtKB/TrEMBL
    A0A8C0TVS4, A0A8I3Q8S8
    Related
    ENSCAFP00845036187.1, ENSCAFT00845046084.1
    Conserved Domains (2) summary
    cd01388
    Location:67 → 138
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam12067
    Location:203 → 253
    Sox17_18_mid; Sox 17/18 central domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049289.1 Alternate UMICH_Zoey_3.1

    Range
    5992409..5994803
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038516271.1 → XP_038372199.1  transcription factor SOX-17

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049770.1 Alternate UNSW_CanFamBas_1.0

    Range
    6198380..6200809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038643486.1 → XP_038499414.1  transcription factor SOX-17

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049250.1 Alternate UU_Cfam_GSD_1.0

    Range
    6377256..6379697
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038579240.1 → XP_038435168.1  LOW QUALITY PROTEIN: transcription factor SOX-17

    UniProtKB/TrEMBL
    A0A8C0TVS4

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006611.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    6289199..6291617
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_544084.6 → XP_544084.4  transcription factor SOX-17

    UniProtKB/TrEMBL
    A0A8C0TVS4, A0A8P0NPN0
    Conserved Domains (2) summary
    cd01388
    Location:67 → 138
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam12067
    Location:203 → 253
    Sox17_18_mid; Sox 17/18 central domain
Nucleotide Protein
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