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ACVR1B activin A receptor type 1B [ Canis lupus familiaris (dog) ]

Gene ID: 486537, updated on 17-Aug-2024

Summary

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Official Symbol
ACVR1Bprovided by VGNC
Official Full Name
activin A receptor type 1Bprovided by VGNC
Primary source
VGNC:VGNC:37562
See related
Ensembl:ENSCAFG00845027407
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See ACVR1B in Genome Data Viewer
Location:
chromosome: 27
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (3006162..3042091, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (43211235..43247173)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (43609429..43645365)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (3022821..3058700, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (3009289..3045207, complement)

Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor subfamily 4 group A member 1 Neighboring gene trafficking regulator and scaffold protein tamalin Neighboring gene uncharacterized LOC119866360 Neighboring gene activin A receptor like type 1 Neighboring gene uncharacterized LOC102153499

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables activin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables activin receptor activity, type I IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of activin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
activin receptor type-1B
XP_005636858.1
XP_038294054.1
XP_038294055.1
XP_038294057.1
XP_038316058.1
XP_038316059.1
XP_038368749.1
XP_038368750.1
XP_038368751.1
XP_038433647.1
XP_038433648.1
XP_038433649.1
XP_038496510.1
XP_038496511.1
XP_038496512.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051831.1 Reference ROS_Cfam_1.0

    Range
    3006162..3042091 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038438126.1 → XP_038294054.1  activin receptor type-1B isoform X1

    UniProtKB/TrEMBL
    A0A8C0P488, A0A8C0QTC6, A0A8I3PWZ3
    Related
    ENSCAFP00845037889.1, ENSCAFT00845048301.1
    Conserved Domains (2) summary
    smart00467
    Location:177 → 207
    GS; GS motif
    cd14143
    Location:211 → 498
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

  2. XM_038438127.1 → XP_038294055.1  activin receptor type-1B isoform X2

    UniProtKB/TrEMBL
    A0A8C0QTC6
    Conserved Domains (2) summary
    smart00467
    Location:148 → 178
    GS; GS motif
    cd14143
    Location:182 → 469
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

  3. XM_038438129.1 → XP_038294057.1  activin receptor type-1B isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTC6
    Related
    ENSCAFP00845037916.1, ENSCAFT00845048330.1
    Conserved Domains (2) summary
    smart00467
    Location:125 → 155
    GS; GS motif
    cd14143
    Location:159 → 446
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049287.1 Alternate UMICH_Zoey_3.1

    Range
    3022821..3058700 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038512821.1 → XP_038368749.1  activin receptor type-1B isoform X1

    Conserved Domains (2) summary
    smart00467
    Location:177 → 207
    GS; GS motif
    cd14143
    Location:211 → 498
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

  2. XM_038512822.1 → XP_038368750.1  activin receptor type-1B isoform X2

    Conserved Domains (2) summary
    smart00467
    Location:148 → 178
    GS; GS motif
    cd14143
    Location:182 → 469
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

  3. XM_038512823.1 → XP_038368751.1  activin receptor type-1B isoform X3

    Conserved Domains (2) summary
    smart00467
    Location:125 → 155
    GS; GS motif
    cd14143
    Location:159 → 446
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

    Range
    3009289..3045207 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038640582.1 → XP_038496510.1  activin receptor type-1B isoform X1

    Conserved Domains (2) summary
    smart00467
    Location:177 → 207
    GS; GS motif
    cd14143
    Location:211 → 498
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

  2. XM_038640583.1 → XP_038496511.1  activin receptor type-1B isoform X2

    Conserved Domains (2) summary
    smart00467
    Location:148 → 178
    GS; GS motif
    cd14143
    Location:182 → 469
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

  3. XM_038640584.1 → XP_038496512.1  activin receptor type-1B isoform X3

    Conserved Domains (2) summary
    smart00467
    Location:125 → 155
    GS; GS motif
    cd14143
    Location:159 → 446
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

    Range
    43609429..43645365
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038577720.1 → XP_038433648.1  activin receptor type-1B isoform X2

    UniProtKB/TrEMBL
    A0A8C0QTC6
    Conserved Domains (2) summary
    smart00467
    Location:148 → 178
    GS; GS motif
    cd14143
    Location:182 → 469
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

  2. XM_038577719.1 → XP_038433647.1  activin receptor type-1B isoform X1

    UniProtKB/TrEMBL
    A0A8C0P488, A0A8C0QTC6, A0A8I3PWZ3
    Conserved Domains (2) summary
    smart00467
    Location:177 → 207
    GS; GS motif
    cd14143
    Location:211 → 498
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

  3. XM_038577721.1 → XP_038433649.1  activin receptor type-1B isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTC6
    Conserved Domains (2) summary
    smart00467
    Location:125 → 155
    GS; GS motif
    cd14143
    Location:159 → 446
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    43211235..43247173
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038460131.1 → XP_038316059.1  activin receptor type-1B isoform X2

    UniProtKB/TrEMBL
    A0A8C0QTC6
    Conserved Domains (2) summary
    smart00467
    Location:148 → 178
    GS; GS motif
    cd14143
    Location:182 → 469
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

  2. XM_038460130.1 → XP_038316058.1  activin receptor type-1B isoform X1

    UniProtKB/TrEMBL
    A0A8C0P488, A0A8C0QTC6, A0A8I3PWZ3
    Conserved Domains (2) summary
    smart00467
    Location:177 → 207
    GS; GS motif
    cd14143
    Location:211 → 498
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors

  3. XM_005636801.4 → XP_005636858.1  activin receptor type-1B isoform X3

    See identical proteins and their annotated locations for XP_005636858.1

    UniProtKB/TrEMBL
    A0A8C0QTC6
    Conserved Domains (2) summary
    smart00467
    Location:125 → 155
    GS; GS motif
    cd14143
    Location:159 → 446
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors
Nucleotide Protein
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