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PI4KA phosphatidylinositol 4-kinase alpha [ Canis lupus familiaris (dog) ]

Gene ID: 486443, updated on 17-Aug-2024

Summary

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Official Symbol
PI4KAprovided by VGNC
Official Full Name
phosphatidylinositol 4-kinase alphaprovided by VGNC
Primary source
VGNC:VGNC:59063
See related
Ensembl:ENSCAFG00845025057
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
PIK4CA
Orthologs
human mouse all
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Genomic context

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See PI4KA in Genome Data Viewer
Location:
chromosome: 26
Exon count:
55
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (32039270..32155774)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (30589065..30707530)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (30798988..30918013)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (30085016..30204201)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (29709699..29828234)

Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111092598 Neighboring gene CRK like proto-oncogene, adaptor protein Neighboring gene synaptosome associated protein 29 Neighboring gene serpin family D member 1 Neighboring gene transmembrane protein 191C Neighboring gene HIC ZBTB transcriptional repressor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol 4-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4-kinase alpha; LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase alpha
Names
phosphatidylinositol 4-kinase, catalytic, alpha polypeptide
XP_038293541.1
XP_038368406.1
XP_038431904.1
XP_038496114.1
XP_543569.7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051830.1 Reference ROS_Cfam_1.0

    Range
    32039270..32155774
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038437613.1 → XP_038293541.1  phosphatidylinositol 4-kinase alpha

    UniProtKB/TrEMBL
    A0A8C0TE10
    Related
    ENSCAFP00845034705.1, ENSCAFT00845044288.1
    Conserved Domains (2) summary
    cd00871
    Location:1548 → 1723
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1784 → 2102
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049286.1 Alternate UMICH_Zoey_3.1

    Range
    30085016..30204201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038512478.1 → XP_038368406.1  phosphatidylinositol 4-kinase alpha

    Conserved Domains (2) summary
    cd00871
    Location:1548 → 1723
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1784 → 2102
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

    Range
    29709699..29828234
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038640186.1 → XP_038496114.1  phosphatidylinositol 4-kinase alpha

    Conserved Domains (2) summary
    cd00871
    Location:1548 → 1723
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1784 → 2102
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

    Range
    30798988..30918013
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038575976.1 → XP_038431904.1  LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase alpha

    UniProtKB/TrEMBL
    A0A8C0TE10
    Conserved Domains (2) summary
    cd00871
    Location:1548 → 1723
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1784 → 2102
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    30589065..30707530
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_543569.8 → XP_543569.7  phosphatidylinositol 4-kinase alpha

    UniProtKB/TrEMBL
    A0A8C0TE10
    Conserved Domains (2) summary
    cd00871
    Location:1548 → 1723
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1784 → 2102
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha
Nucleotide Protein
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