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Hsp70Bb Heat shock protein 70 Bb [ Drosophila melanogaster (fruit fly) ]

Gene ID: 48582, updated on 28-Oct-2024

Summary

Official Symbol
Hsp70Bbprovided by FlyBase
Official Full Name
Heat shock protein 70 Bbprovided by FlyBase
Primary source
FLYBASE:FBgn0013278
Locus tag
Dmel_CG31359
See related
AllianceGenome:FB:FBgn0013278
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Bb; CG31359; dhsp70; dHsp70; Dm-hsp70; Dmel\CG31359; DMHSP7D1; Hsp 70; hsp-70; Hsp-70; hsp70; Hsp70; HSP70; hsp70 87C; Hsp70(87C); Hsp70A7d; hsp70B; Hsp70B; hsp70Bb; Hsp70bb; HSP70Bb; Hsp70Bbc; Hsp70Bc; HSP70cA4
Summary
Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Involved in heat shock-mediated polytene chromosome puffing and response to hypoxia. Predicted to be active in cytoplasm and nucleus. Is expressed in egg chamber; organism; and spermatozoon. [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

See Hsp70Bb in Genome Data Viewer
Location:
87B14-87B14; 3-52 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12505793..12508139)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8331515..8333861)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Heat shock protein 70 Bbb Neighboring gene pseudo Neighboring gene pseudo Neighboring gene Heat shock protein 70 Bc

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ATP-dependent protein folding chaperone IEA
Inferred from Electronic Annotation
more info
 
enables heat shock protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein folding chaperone IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in chaperone cofactor-dependent protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in heat shock-mediated polytene chromosome puffing IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in response to heat IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to heat NAS
Non-traceable Author Statement
more info
PubMed 
involved_in response to hypoxia IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to hypoxia IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to unfolded protein NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
heat shock protein 70 Bb
Names
70 kDa heat shock protein, cytosolic A 4
87C locus
CG31359-PA
Heat-shock-protein-70Bb
Hsp70Bb-PA
heat shock protein 70
heat-shock protein 70
protein 70

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12505793..12508139
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080188.3NP_524927.2  heat shock protein 70 Bb [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524927.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B0BNN7, P02824, Q53XF0, Q5I7H2, Q5I7H4, Q5I7H6, Q5I7H8, Q5I7I3, Q5I7I6, Q5I7I8, Q8INI8, Q95NK0, Q95W08, Q9BIR7, Q9BIR8, Q9BIR9, Q9BIS0, Q9BIS1, Q9BIS2, Q9BIS3, Q9BIS4, Q9I7J6
    UniProtKB/TrEMBL
    F3YDI6
    Related
    FBpp0082106
    Conserved Domains (2) summary
    cd10233
    Location:3379
    HSPA1-2_6-8-like_NBD; Nucleotide-binding domain of HSPA1-A, -B, -L, HSPA-2, -6, -7, -8, and similar proteins
    PTZ00009
    Location:2641
    PTZ00009; heat shock 70 kDa protein; Provisional