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EXOG exo/endonuclease G [ Canis lupus familiaris (dog) ]

Gene ID: 485591, updated on 17-Aug-2024

Summary

Official Symbol
EXOGprovided by VGNC
Official Full Name
exo/endonuclease Gprovided by VGNC
Primary source
VGNC:VGNC:40520
See related
Ensembl:ENSCAFG00845030066
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
ENDOGL1
Orthologs
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Genomic context

See EXOG in Genome Data Viewer
Location:
chromosome: 23
Exon count:
13
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 23 NC_051827.1 (8520487..8549097)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 23 NC_006605.4 (8271601..8300194)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 23 NC_049244.1 (8468262..8496874)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 23 NC_049283.1 (8334334..8362914)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 23 NC_049764.1 (8474827..8503623)

Chromosome 23 - NC_051827.1Genomic Context describing neighboring genes Neighboring gene xylulokinase Neighboring gene activin A receptor type 2B Neighboring gene uncharacterized LOC119865347 Neighboring gene 40S ribosomal protein S2-like Neighboring gene sodium voltage-gated channel alpha subunit 5

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-3' exonuclease activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables RNA endonuclease activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables single-stranded DNA endodeoxyribonuclease activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in apoptotic DNA fragmentation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
nuclease EXOG, mitochondrial
Names
endo/exonuclease (5'-3'), endonuclease G-like
endonuclease G-like 1
XP_005634310.1
XP_038287844.1
XP_038287845.1
XP_038363157.1
XP_038363158.1
XP_038426397.1
XP_038426398.1
XP_038490575.1
XP_038490576.1
XP_542710.4

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051827.1 Reference ROS_Cfam_1.0

    Range
    8520487..8549097
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038431916.1XP_038287844.1  nuclease EXOG, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0LNM2, A0A8C0T3T9, A0A8I3Q2Y5
    Related
    ENSCAFP00845041844.1, ENSCAFT00845053280.1
    Conserved Domains (2) summary
    smart00477
    Location:107316
    NUC; DNA/RNA non-specific endonuclease
    pfam18026
    Location:332380
    Exog_C; Endo/exonuclease (EXOG) C-terminal domain
  2. XM_038431917.1XP_038287845.1  nuclease EXOG, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0Z140, A0A8I3QAA7
    Related
    ENSCAFP00845041838.1, ENSCAFT00845053273.1
    Conserved Domains (2) summary
    smart00477
    Location:83266
    NUC; DNA/RNA non-specific endonuclease
    pfam18026
    Location:282330
    Exog_C; Endo/exonuclease (EXOG) C-terminal domain

RNA

  1. XR_005299978.1 RNA Sequence

  2. XR_005299976.1 RNA Sequence

  3. XR_005299977.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049283.1 Alternate UMICH_Zoey_3.1

    Range
    8334334..8362914
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038507229.1XP_038363157.1  nuclease EXOG, mitochondrial isoform X1

    Conserved Domains (2) summary
    smart00477
    Location:107316
    NUC; DNA/RNA non-specific endonuclease
    pfam18026
    Location:332380
    Exog_C; Endo/exonuclease (EXOG) C-terminal domain
  2. XM_038507230.1XP_038363158.1  nuclease EXOG, mitochondrial isoform X2

    Conserved Domains (2) summary
    smart00477
    Location:83266
    NUC; DNA/RNA non-specific endonuclease
    pfam18026
    Location:282330
    Exog_C; Endo/exonuclease (EXOG) C-terminal domain

RNA

  1. XR_005343073.1 RNA Sequence

  2. XR_005343071.1 RNA Sequence

  3. XR_005343072.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049764.1 Alternate UNSW_CanFamBas_1.0

    Range
    8474827..8503623
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038634647.1XP_038490575.1  nuclease EXOG, mitochondrial isoform X1

  2. XM_038634648.1XP_038490576.1  nuclease EXOG, mitochondrial isoform X2

RNA

  1. XR_005410796.1 RNA Sequence

  2. XR_005410797.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049244.1 Alternate UU_Cfam_GSD_1.0

    Range
    8468262..8496874
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038570469.1XP_038426397.1  nuclease EXOG, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0LNM2, A0A8C0T3T9, A0A8I3Q2Y5
    Conserved Domains (2) summary
    smart00477
    Location:107316
    NUC; DNA/RNA non-specific endonuclease
    pfam18026
    Location:332380
    Exog_C; Endo/exonuclease (EXOG) C-terminal domain
  2. XM_038570470.1XP_038426398.1  nuclease EXOG, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0Z140, A0A8I3QAA7
    Conserved Domains (2) summary
    smart00477
    Location:83266
    NUC; DNA/RNA non-specific endonuclease
    pfam18026
    Location:282330
    Exog_C; Endo/exonuclease (EXOG) C-terminal domain

RNA

  1. XR_005376855.1 RNA Sequence

  2. XR_005376853.1 RNA Sequence

  3. XR_005376854.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006605.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    8271601..8300194
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005634253.4XP_005634310.1  nuclease EXOG, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0LNM2, A0A8C0T3T9, A0A8I3Q2Y5
    Conserved Domains (2) summary
    smart00477
    Location:107316
    NUC; DNA/RNA non-specific endonuclease
    pfam18026
    Location:332380
    Exog_C; Endo/exonuclease (EXOG) C-terminal domain
  2. XM_542710.7XP_542710.4  nuclease EXOG, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0Z140, A0A8I3QAA7
    Conserved Domains (2) summary
    smart00477
    Location:83266
    NUC; DNA/RNA non-specific endonuclease
    pfam18026
    Location:282330
    Exog_C; Endo/exonuclease (EXOG) C-terminal domain

RNA

  1. XR_005313962.1 RNA Sequence

  2. XR_002618040.2 RNA Sequence

  3. XR_002618041.2 RNA Sequence