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PLCD1 phospholipase C delta 1 [ Canis lupus familiaris (dog) ]

Gene ID: 485586, updated on 17-Aug-2024

Summary

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Official Symbol
PLCD1provided by VGNC
Official Full Name
phospholipase C delta 1provided by VGNC
Primary source
VGNC:VGNC:44647
See related
Ensembl:ENSCAFG00845029321
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See PLCD1 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 23 NC_051827.1 (8071728..8094058, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 23 NC_006605.4 (7824568..7846894, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 23 NC_049244.1 (8019585..8041935, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 23 NC_049283.1 (7886045..7908371, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 23 NC_049764.1 (8027176..8049514, complement)

Chromosome 23 - NC_051827.1Genomic Context describing neighboring genes Neighboring gene CTD small phosphatase like Neighboring gene microRNA mir-26a-1 Neighboring gene villin like Neighboring gene uncharacterized LOC119865346 Neighboring gene DLEC1 cilia and flagella associated protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
XP_038287815.1
XP_038287816.1
XP_038363127.1
XP_038363128.1
XP_038426367.1
XP_038426368.1
XP_038490546.1
XP_038490547.1
XP_542705.3
XP_859460.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051827.1 Reference ROS_Cfam_1.0

    Range
    8071728..8094058 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038431888.1 → XP_038287816.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SY56
    Related
    ENSCAFP00845040730.1, ENSCAFT00845051912.1
    Conserved Domains (4) summary
    cd00275
    Location:629 → 755
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:295 → 596
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    cd13363
    Location:22 → 139
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cd16217
    Location:144 → 283
    EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)

  2. XM_038431887.1 → XP_038287815.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0SY56, A0A8I3Q831
    Related
    ENSCAFP00845040811.1, ENSCAFT00845052021.1
    Conserved Domains (4) summary
    cd00275
    Location:650 → 776
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:316 → 617
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    cd13363
    Location:43 → 160
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cd16217
    Location:165 → 304
    EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049283.1 Alternate UMICH_Zoey_3.1

    Range
    7886045..7908371 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038507200.1 → XP_038363128.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X2

  2. XM_038507199.1 → XP_038363127.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049764.1 Alternate UNSW_CanFamBas_1.0

    Range
    8027176..8049514 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038634619.1 → XP_038490547.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X2

  2. XM_038634618.1 → XP_038490546.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1

    Conserved Domains (4) summary
    cd00275
    Location:650 → 776
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:316 → 617
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    cd13363
    Location:43 → 160
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cd16217
    Location:165 → 304
    EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049244.1 Alternate UU_Cfam_GSD_1.0

    Range
    8019585..8041935 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038570440.1 → XP_038426368.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SY56

  2. XM_038570439.1 → XP_038426367.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JKV3, A0A8C0MWF1, A0A8C0SY56
    Conserved Domains (4) summary
    cd00275
    Location:650 → 776
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:316 → 617
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    cd13363
    Location:43 → 160
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cd16217
    Location:165 → 304
    EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006605.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    7824568..7846894 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_854367.5 → XP_859460.4  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SY56
    Conserved Domains (4) summary
    cd00275
    Location:629 → 755
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:295 → 596
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    cd13363
    Location:22 → 139
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cd16217
    Location:144 → 283
    EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)

  2. XM_542705.7 → XP_542705.3  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0SY56, A0A8P0SR17
    Conserved Domains (4) summary
    cd00275
    Location:650 → 776
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:316 → 617
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    cd13363
    Location:43 → 160
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cd16217
    Location:165 → 304
    EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)
Nucleotide Protein
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