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PLEKHA4 pleckstrin homology domain containing A4 [ Canis lupus familiaris (dog) ]

Gene ID: 484393, updated on 17-Aug-2024

Summary

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Official Symbol
PLEKHA4provided by VGNC
Official Full Name
pleckstrin homology domain containing A4provided by VGNC
Primary source
VGNC:VGNC:53751
See related
Ensembl:ENSCAFG00845000635
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See PLEKHA4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
20
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (108016407..108042600)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (107014258..107040442)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (108165850..108192037)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (107683365..107709534)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (107330227..107356423)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene nucleobindin 1 Neighboring gene TUB like protein 2 Neighboring gene protein phosphatase 1 regulatory subunit 15A Neighboring gene hydroxysteroid 17-beta dehydrogenase 14 Neighboring gene uncharacterized LOC102157107 Neighboring gene branched chain amino acid transaminase 2 Neighboring gene fibroblast growth factor 21

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Light-activated BioID - an optically activated proximity labeling system to study protein-protein interactions. Shafraz O, et al. J Cell Sci, 2023 Oct 1. PMID 37756605, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

General protein information

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Preferred Names
pleckstrin homology domain-containing family A member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    108016407..108042600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038656399.1 → XP_038512327.1  pleckstrin homology domain-containing family A member 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LR93, A0A8I3ME40, A0A8P0NUF7
    Related
    ENSCAFP00845000791.1, ENSCAFT00845001043.1
    Conserved Domains (2) summary
    COG1196
    Location:360 → 468
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  2. XM_038656400.1 → XP_038512328.1  pleckstrin homology domain-containing family A member 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LR93, A0A8C0PM58
    Conserved Domains (2) summary
    COG1196
    Location:336 → 444
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  3. XM_038656401.1 → XP_038512329.1  pleckstrin homology domain-containing family A member 4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LR93
    Conserved Domains (2) summary
    COG1196
    Location:323 → 431
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  4. XM_038656402.1 → XP_038512330.1  pleckstrin homology domain-containing family A member 4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LR93
    Conserved Domains (2) summary
    COG1196
    Location:233 → 341
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl17171
    Location:2 → 25
    PH-like; Pleckstrin homology-like domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    107683365..107709534
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038467604.1 → XP_038323532.1  pleckstrin homology domain-containing family A member 4 isoform X1

    Conserved Domains (2) summary
    COG1196
    Location:360 → 468
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  2. XM_038467605.1 → XP_038323533.1  pleckstrin homology domain-containing family A member 4 isoform X2

    Conserved Domains (2) summary
    COG1196
    Location:336 → 444
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  3. XM_038467606.1 → XP_038323534.1  pleckstrin homology domain-containing family A member 4 isoform X3

    Conserved Domains (2) summary
    COG1196
    Location:323 → 431
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  4. XM_038467607.1 → XP_038323535.1  pleckstrin homology domain-containing family A member 4 isoform X4

    Conserved Domains (2) summary
    COG1196
    Location:233 → 341
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl17171
    Location:2 → 25
    PH-like; Pleckstrin homology-like domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    107330227..107356423
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038592608.1 → XP_038448536.1  pleckstrin homology domain-containing family A member 4 isoform X1

    Conserved Domains (2) summary
    COG1196
    Location:360 → 468
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  2. XM_038592610.1 → XP_038448538.1  pleckstrin homology domain-containing family A member 4 isoform X2

    Conserved Domains (2) summary
    COG1196
    Location:336 → 444
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  3. XM_038592611.1 → XP_038448539.1  pleckstrin homology domain-containing family A member 4 isoform X3

    Conserved Domains (2) summary
    COG1196
    Location:323 → 431
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  4. XM_038592612.1 → XP_038448540.1  pleckstrin homology domain-containing family A member 4 isoform X4

    Conserved Domains (2) summary
    COG1196
    Location:233 → 341
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl17171
    Location:2 → 25
    PH-like; Pleckstrin homology-like domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    108165850..108192037
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038528318.1 → XP_038384246.1  pleckstrin homology domain-containing family A member 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LR93, A0A8I3ME40, A0A8P0NUF7
    Conserved Domains (2) summary
    COG1196
    Location:360 → 468
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  2. XM_038528319.1 → XP_038384247.1  pleckstrin homology domain-containing family A member 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LR93, A0A8C0PM58
    Conserved Domains (2) summary
    COG1196
    Location:336 → 444
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  3. XM_038528320.1 → XP_038384248.1  pleckstrin homology domain-containing family A member 4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LR93
    Conserved Domains (2) summary
    COG1196
    Location:323 → 431
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  4. XM_038528321.1 → XP_038384249.1  pleckstrin homology domain-containing family A member 4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LR93
    Conserved Domains (2) summary
    COG1196
    Location:233 → 341
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl17171
    Location:2 → 25
    PH-like; Pleckstrin homology-like domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    107014258..107040442
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038678089.1 → XP_038534017.1  pleckstrin homology domain-containing family A member 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LR93, A0A8I3ME40, A0A8P0NUF7
    Conserved Domains (2) summary
    COG1196
    Location:360 → 468
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  2. XM_038678150.1 → XP_038534078.1  pleckstrin homology domain-containing family A member 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LR93, A0A8C0PM58
    Conserved Domains (2) summary
    COG1196
    Location:336 → 444
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  3. XM_038678231.1 → XP_038534159.1  pleckstrin homology domain-containing family A member 4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LR93
    Conserved Domains (2) summary
    COG1196
    Location:323 → 431
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13248
    Location:49 → 152
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

  4. XM_038678313.1 → XP_038534241.1  pleckstrin homology domain-containing family A member 4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LR93
    Conserved Domains (2) summary
    COG1196
    Location:233 → 341
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl17171
    Location:2 → 25
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
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