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TMTC2 transmembrane O-mannosyltransferase targeting cadherins 2 [ Canis lupus familiaris (dog) ]

Gene ID: 482584, updated on 17-Aug-2024

Summary

Official Symbol
TMTC2provided by VGNC
Official Full Name
transmembrane O-mannosyltransferase targeting cadherins 2provided by VGNC
Primary source
VGNC:VGNC:47639
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
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Genomic context

See TMTC2 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (25377180..25529388)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (25060632..25448131)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (24585728..24973537)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119869291 Neighboring gene protein O-mannosyl-transferase TMTC2 Neighboring gene U12 minor spliceosomal RNA Neighboring gene uncharacterized LOC111099026 Neighboring gene uncharacterized LOC119869287 Neighboring gene uncharacterized LOC111098890

Genomic regions, transcripts, and products

General protein information

Preferred Names
protein O-mannosyl-transferase TMTC2
Names
transmembrane and tetratricopeptide repeat containing 2
XP_022283845.2
XP_038307613.1
XP_038352102.1
XP_038352103.1
XP_038352104.1
XP_038544727.1
XP_539701.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    25377180..25529388
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038688799.1XP_038544727.1  protein O-mannosyl-transferase TMTC2 isoform X1

    Conserved Domains (2) summary
    COG0457
    Location:56253
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:131157
    TPR; TPR repeat [structural motif]

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    24585728..24973537
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038496175.1XP_038352103.1  protein O-mannosyl-transferase TMTC2 isoform X3

    Conserved Domains (3) summary
    COG0457
    Location:481722
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:527555
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:248317
    DUF1736; Domain of unknown function (DUF1736)
  2. XM_038496174.1XP_038352102.1  protein O-mannosyl-transferase TMTC2 isoform X2

    Conserved Domains (4) summary
    COG0457
    Location:481722
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    COG5010
    Location:643823
    TadD; Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures]
    sd00006
    Location:527555
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:248317
    DUF1736; Domain of unknown function (DUF1736)
  3. XM_038496176.1XP_038352104.1  protein O-mannosyl-transferase TMTC2 isoform X4

    Conserved Domains (4) summary
    COG0457
    Location:236467
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    COG5010
    Location:398578
    TadD; Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures]
    sd00006
    Location:282310
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:372
    DUF1736; Domain of unknown function (DUF1736)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    25060632..25448131
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022428137.2XP_022283845.2  protein O-mannosyl-transferase TMTC2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0P6K7, A0A8C0SJB6, A0A8P0N8N3
    Conserved Domains (3) summary
    COG0457
    Location:481722
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:527555
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:248317
    DUF1736; Domain of unknown function (DUF1736)
  2. XM_539701.7XP_539701.4  protein O-mannosyl-transferase TMTC2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0NX25, A0A8C0SHC6, A0A8I3RYI9
    Conserved Domains (4) summary
    COG0457
    Location:481722
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    COG5010
    Location:643823
    TadD; Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures]
    sd00006
    Location:527555
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:248317
    DUF1736; Domain of unknown function (DUF1736)
  3. XM_038451685.1XP_038307613.1  protein O-mannosyl-transferase TMTC2 isoform X7

    Conserved Domains (4) summary
    COG0457
    Location:236467
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    COG5010
    Location:398578
    TadD; Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures]
    sd00006
    Location:282310
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:372
    DUF1736; Domain of unknown function (DUF1736)