TMPRSS11A transmembrane serine protease 11A [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: TMPRSS11Aprovided by VGNC
Official Full Name: transmembrane serine protease 11Aprovided by VGNC
Primary source: VGNC:VGNC:47628
See related: Ensembl:ENSCAFG00845008712
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 13

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	13	NC_051817.1 (59128326..59158878, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	13	NC_006595.4 (58349009..58384157, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	13	NC_049234.1 (59272292..59307463, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	13	NC_049273.1 (58771278..58806522, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	13	NC_049754.1 (58266629..58317564, complement)

Chromosome 13 - NC_051817.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: transmembrane protease serine 11A; LOW QUALITY PROTEIN: transmembrane protease serine 11A

Names: transmembrane protease, serine 11A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051817.1 Reference ROS_Cfam_1.0

Range

59128326..59158878 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038684564.1 → XP_038540492.1 LOW QUALITY PROTEIN: transmembrane protease serine 11A isoform X1

UniProtKB/TrEMBL

A0A8I3N9N9

Related

ENSCAFP00845011898.1, ENSCAFT00845015324.1

Conserved Domains (2) summary

cd00190
Location:198 → 423

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

pfam01390
Location:48 → 162

SEA; SEA domain

Alternate UMICH_Zoey_3.1

Genomic

NC_049273.1 Alternate UMICH_Zoey_3.1

Range

58771278..58806522 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038492845.1 → XP_038348773.1 transmembrane protease serine 11A isoform X2

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049754.1 Alternate UNSW_CanFamBas_1.0

Range

58266629..58317564 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038618958.1 → XP_038474886.1 LOW QUALITY PROTEIN: transmembrane protease serine 11A isoform X3

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049234.1 Alternate UU_Cfam_GSD_1.0

Range

59272292..59307463 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038555080.1 → XP_038411008.1 LOW QUALITY PROTEIN: transmembrane protease serine 11A isoform X4

UniProtKB/TrEMBL

A0A8I3N9N9

Conserved Domains (2) summary

cd00190
Location:198 → 423

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

pfam01390
Location:48 → 162

SEA; SEA domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

58349009..58384157 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038689010.1 → XP_038544938.1 LOW QUALITY PROTEIN: transmembrane protease serine 11A isoform X5

UniProtKB/TrEMBL

A0A8I3N9N9

Conserved Domains (2) summary

cd00190
Location:198 → 423

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

pfam01390
Location:48 → 162

SEA; SEA domain