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RNF8 ring finger protein 8 [ Canis lupus familiaris (dog) ]

Gene ID: 481775, updated on 17-Aug-2024

Summary

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Official Symbol
RNF8provided by VGNC
Official Full Name
ring finger protein 8provided by VGNC
Primary source
VGNC:VGNC:45676
See related
Ensembl:ENSCAFG00845010951
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See RNF8 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (6844755..6879956)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (6398291..6433355)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (6562602..6597564)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (6381196..6416424)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (6463623..6498627)

Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein G-like Neighboring gene transmembrane protein 217 Neighboring gene TBC1 domain family member 22B Neighboring gene U1 small nuclear ribonucleoprotein C-like Neighboring gene uncharacterized LOC102156054 Neighboring gene cap methyltransferase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K48-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in site of double-strand break IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase RNF8
XP_038347615.1
XP_038409844.1
XP_038473704.1
XP_038539301.1
XP_864730.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051816.1 Reference ROS_Cfam_1.0

    Range
    6844755..6879956
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038683373.1 → XP_038539301.1  E3 ubiquitin-protein ligase RNF8

    UniProtKB/TrEMBL
    A0A8C0MWH3, A0A8C0QWT5, A0A8C0T933, A0A8P0S7J0
    Related
    ENSCAFP00845015287.1, ENSCAFT00845019547.1
    Conserved Domains (3) summary
    cd00060
    Location:17 → 110
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02169
    Location:257 → 394
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    cd16535
    Location:402 → 443
    RING-HC_RNF8; RING finger, HC subclass, found in RING finger protein 8 (RNF8) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049272.1 Alternate UMICH_Zoey_3.1

    Range
    6381196..6416424
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038491687.1 → XP_038347615.1  E3 ubiquitin-protein ligase RNF8

    Conserved Domains (3) summary
    cd00060
    Location:17 → 110
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02169
    Location:257 → 394
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    cd16535
    Location:402 → 443
    RING-HC_RNF8; RING finger, HC subclass, found in RING finger protein 8 (RNF8) and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

    Range
    6463623..6498627
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038617776.1 → XP_038473704.1  E3 ubiquitin-protein ligase RNF8

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

    Range
    6562602..6597564
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038553916.1 → XP_038409844.1  E3 ubiquitin-protein ligase RNF8

    UniProtKB/TrEMBL
    A0A8C0MWH3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    6398291..6433355
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_859637.6 → XP_864730.1  E3 ubiquitin-protein ligase RNF8

    UniProtKB/TrEMBL
    A0A8C0MWH3, A0A8C0QWT5, A0A8C0T933, A0A8P0S7J0
    Conserved Domains (3) summary
    cd00060
    Location:17 → 110
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02169
    Location:257 → 394
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    cd16535
    Location:402 → 443
    RING-HC_RNF8; RING finger, HC subclass, found in RING finger protein 8 (RNF8) and similar proteins
Nucleotide Protein
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