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PPARD peroxisome proliferator activated receptor delta [ Canis lupus familiaris (dog) ]

Gene ID: 481756, updated on 5-Mar-2024

Summary

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Official Symbol
PPARDprovided by VGNC
Official Full Name
peroxisome proliferator activated receptor deltaprovided by VGNC
Primary source
VGNC:VGNC:44835
See related
Ensembl:ENSCAFG00845028955
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
PPAR-beta; PPAR-delta
Orthologs
human mouse all
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Genomic context

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See PPARD in Genome Data Viewer
Location:
chromosome: 12
Exon count:
13
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (4830969..4918771)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (4582161..4595131)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (4744188..4757152)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (4565298..4578271)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (4643973..4656940)

Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 76 Neighboring gene DEF6 guanine nucleotide exchange factor Neighboring gene FA complementation group E Neighboring gene ribosomal protein L10a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning, expression and investigation for polymorphisms of canine peroxisome proliferator-activated receptors. Nishii N, et al. Comp Biochem Physiol B Biochem Mol Biol, 2007 Aug. PMID 17512769

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Expression of PPARbeta showed only small variations during canine adipocyte differentiation.
    Title: Cloning, expression and investigation for polymorphisms of canine peroxisome proliferator-activated receptors.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hormone-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peroxisome proliferator-activated receptor delta
Names
nuclear receptor subfamily 1 group C member 2
peroxisome proliferative activated receptor, delta
peroxisome proliferator-activated receptor beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001048102.1 → NP_001041567.1  peroxisome proliferator-activated receptor delta

    See identical proteins and their annotated locations for NP_001041567.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ648277
    UniProtKB/Swiss-Prot
    Q0ZAQ8
    UniProtKB/TrEMBL
    A0A8C0K2K4, A0A8C0NFH2, A0A8I3PZ92
    Conserved Domains (2) summary
    cd06932
    Location:173 → 440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73 → 156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051816.1 Reference ROS_Cfam_1.0

    Range
    4830969..4918771
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038682756.1 → XP_038538684.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    Q0ZAQ8
    UniProtKB/TrEMBL
    A0A8C0K2K4, A0A8C0NFH2, A0A8I3PZ92
    Related
    ENSCAFP00845040209.1, ENSCAFT00845051265.1
    Conserved Domains (2) summary
    cd06932
    Location:173 → 440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73 → 156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

  2. XM_038682760.1 → XP_038538688.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    Q0ZAQ8
    UniProtKB/TrEMBL
    A0A8C0K2K4, A0A8C0NFH2, A0A8I3PZ92
    Conserved Domains (2) summary
    cd06932
    Location:173 → 440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73 → 156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

  3. XM_038682757.1 → XP_038538685.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    Q0ZAQ8
    UniProtKB/TrEMBL
    A0A8C0K2K4, A0A8C0NFH2, A0A8I3PZ92
    Conserved Domains (2) summary
    cd06932
    Location:173 → 440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73 → 156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

  4. XM_038682759.1 → XP_038538687.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    Q0ZAQ8
    UniProtKB/TrEMBL
    A0A8C0K2K4, A0A8C0NFH2, A0A8I3PZ92
    Conserved Domains (2) summary
    cd06932
    Location:173 → 440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73 → 156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

  5. XM_038682758.1 → XP_038538686.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    Q0ZAQ8
    UniProtKB/TrEMBL
    A0A8C0K2K4, A0A8C0NFH2, A0A8I3PZ92
    Conserved Domains (2) summary
    cd06932
    Location:173 → 440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73 → 156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049272.1 Alternate UMICH_Zoey_3.1

    Range
    4565298..4578271
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

    Range
    4643973..4656940
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

    Range
    4744188..4757152
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    4582161..4595131
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0ZAQ8.1 GenPept UniProtKB/Swiss-Prot:Q0ZAQ8

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