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L3MBTL2 L3MBTL histone methyl-lysine binding protein 2 [ Canis lupus familiaris (dog) ]

Gene ID: 481235, updated on 17-Aug-2024

Summary

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Official Symbol
L3MBTL2provided by VGNC
Official Full Name
L3MBTL histone methyl-lysine binding protein 2provided by VGNC
Primary source
VGNC:VGNC:42558
See related
Ensembl:ENSCAFG00845017974
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See L3MBTL2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (24744975..24766229, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (23932676..23953922, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (24956795..24978045, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (24461399..24482648, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (24782259..24803509, complement)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH-type containing 7B Neighboring gene Ran GTPase activating protein 1 Neighboring gene chondroadherin like Neighboring gene uncharacterized LOC102155369 Neighboring gene small nucleolar RNA U13 Neighboring gene U6 spliceosomal RNA Neighboring gene E1A binding protein p300

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables methylated histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lethal(3)malignant brain tumor-like protein 2
Names
L3MBTL2, polycomb repressive complex 1 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    24744975..24766229 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038679752.1 → XP_038535680.1  lethal(3)malignant brain tumor-like protein 2

    UniProtKB/TrEMBL
    A0A8C0P5D6
    Related
    ENSCAFP00845024908.1, ENSCAFT00845031834.1
    Conserved Domains (2) summary
    smart00561
    Location:515 → 606
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    pfam02820
    Location:435 → 506
    MBT; mbt repeat

RNA

  1. XR_005433349.1 RNA Sequence

    Related
    ENSCAFT00845031954.1

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    24461399..24482648 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038488516.1 → XP_038344444.1  lethal(3)malignant brain tumor-like protein 2

RNA

  1. XR_005331854.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    24782259..24803509 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038614411.1 → XP_038470339.1  lethal(3)malignant brain tumor-like protein 2

RNA

  1. XR_005399993.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    24956795..24978045 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038550445.1 → XP_038406373.1  lethal(3)malignant brain tumor-like protein 2

    UniProtKB/TrEMBL
    A0A8C0P5D6, A0A8C0T329

RNA

  1. XR_005365553.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    23932676..23953922 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_538356.7 → XP_538356.2  lethal(3)malignant brain tumor-like protein 2

    UniProtKB/TrEMBL
    A0A8C0P5D6, A0A8C0T329
    Conserved Domains (2) summary
    smart00561
    Location:515 → 606
    MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    pfam02820
    Location:435 → 506
    MBT; mbt repeat

RNA

  1. XR_293337.4 RNA Sequence

Nucleotide Protein
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