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CASK calcium/calmodulin dependent serine protein kinase [ Canis lupus familiaris (dog) ]

Gene ID: 480887, updated on 17-Aug-2024

Summary

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Official Symbol
CASKprovided by VGNC
Official Full Name
calcium/calmodulin dependent serine protein kinaseprovided by VGNC
Primary source
VGNC:VGNC:38729
See related
Ensembl:ENSCAFG00845025610
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See CASK in Genome Data Viewer
Location:
chromosome: X
Exon count:
27
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (35992809..36371502, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (23287445..23579098, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (36082753..36433406, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (36067274..36417597, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (36039464..36395455, complement)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC491837 Neighboring gene nyctalopin Neighboring gene G protein-coupled receptor 34 Neighboring gene G protein-coupled receptor 82 Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC106558482

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The interaction between CASK and the tumour suppressor Dlg1 regulates mitotic spindle orientation in mammalian epithelia. Porter AP, et al. J Cell Sci, 2019 Jul 15. PMID 31289196, Free PMC Article
  2. The structural evolution of a P2Y-like G-protein-coupled receptor. Schulz A, et al. J Biol Chem, 2003 Sep 12. PMID 12835326
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These results establish the importance of the CASK-Dlg1 interaction in oriented cell division and epithelial integrity.
    Title: The interaction between CASK and the tumour suppressor Dlg1 regulates mitotic spindle orientation in mammalian epithelia.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurotransmitter secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peripheral plasma membrane protein CASK
Names
G-protein-coupled receptor GPR34
XP_038305728.1
XP_038305730.1
XP_038305731.1
XP_038305732.1
XP_038320708.1
XP_038379174.1
XP_038379175.1
XP_038379176.1
XP_038379177.1
XP_038379178.1
XP_038379179.1
XP_038379180.1
XP_038379181.1
XP_038379182.1
XP_038379183.1
XP_038379184.1
XP_038379185.1
XP_038443137.1
XP_038443138.1
XP_038443139.1
XP_038443140.1
XP_038443141.1
XP_038443142.1
XP_038443143.1
XP_038443144.1
XP_038443146.1
XP_038443147.1
XP_038443148.1
XP_038443149.1
XP_038507653.1
XP_038507655.1
XP_038507656.1
XP_038507657.1
XP_038507658.1
XP_038507659.1
XP_038507660.1
XP_038507661.1
XP_038507662.1
XP_038507663.1
XP_038507664.1
XP_038507665.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    35992809..36371502 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038449802.1 → XP_038305730.1  peripheral plasma membrane protein CASK isoform X2

    UniProtKB/TrEMBL
    A0A8C0SHD4, A0A8I3PQD3
    Related
    ENSCAFP00845036809.1, ENSCAFT00845046925.1
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:733 → 906
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  2. XM_038449803.1 → XP_038305731.1  peripheral plasma membrane protein CASK isoform X3

    UniProtKB/TrEMBL
    A0A8C0NDJ2
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:593 → 654
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:710 → 883
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  3. XM_038449800.1 → XP_038305728.1  peripheral plasma membrane protein CASK isoform X1

    UniProtKB/TrEMBL
    A0A8C0SHD4, A0A8I3PQD3
    Related
    ENSCAFP00845036144.1, ENSCAFT00845046038.1
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:738 → 911
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  4. XM_038449804.1 → XP_038305732.1  peripheral plasma membrane protein CASK isoform X4

    UniProtKB/TrEMBL
    A0A8P0NQ62
    Related
    ENSCAFP00845036576.1, ENSCAFT00845046589.1
    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:587 → 648
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:709 → 882
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    36067274..36417597 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038523247.1 → XP_038379175.1  peripheral plasma membrane protein CASK isoform X6

    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:622 → 683
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:739 → 912
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  2. XM_038523256.1 → XP_038379184.1  peripheral plasma membrane protein CASK isoform X11

    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:587 → 648
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:709 → 882
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  3. XM_038523253.1 → XP_038379181.1  peripheral plasma membrane protein CASK isoform X10

    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:599 → 660
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:721 → 894
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  4. XM_038523252.1 → XP_038379180.1  peripheral plasma membrane protein CASK isoform X9

    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:610 → 671
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:732 → 905
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  5. XM_038523246.1 → XP_038379174.1  peripheral plasma membrane protein CASK isoform X5

    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:622 → 683
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:744 → 917
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  6. XM_038523249.1 → XP_038379177.1  peripheral plasma membrane protein CASK isoform X7

    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:738 → 911
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  7. XM_038523248.1 → XP_038379176.1  peripheral plasma membrane protein CASK isoform X1

    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:738 → 911
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  8. XM_038523257.1 → XP_038379185.1  peripheral plasma membrane protein CASK isoform X12

    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:575 → 636
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:692 → 865
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  9. XM_038523251.1 → XP_038379179.1  peripheral plasma membrane protein CASK isoform X8

    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:610 → 671
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:732 → 905
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  10. XM_038523255.1 → XP_038379183.1  peripheral plasma membrane protein CASK isoform X4

    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:587 → 648
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:709 → 882
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  11. XM_038523254.1 → XP_038379182.1  peripheral plasma membrane protein CASK isoform X3

    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:593 → 654
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:710 → 883
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  12. XM_038523250.1 → XP_038379178.1  peripheral plasma membrane protein CASK isoform X2

    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:733 → 906
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    36039464..36395455 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038651727.1 → XP_038507655.1  peripheral plasma membrane protein CASK isoform X14

    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:622 → 683
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:739 → 912
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  2. XM_038651736.1 → XP_038507664.1  peripheral plasma membrane protein CASK isoform X19

    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:587 → 648
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:709 → 882
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  3. XM_038651733.1 → XP_038507661.1  peripheral plasma membrane protein CASK isoform X18

    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:599 → 660
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:721 → 894
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  4. XM_038651732.1 → XP_038507660.1  peripheral plasma membrane protein CASK isoform X17

    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:610 → 671
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:732 → 905
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  5. XM_038651725.1 → XP_038507653.1  peripheral plasma membrane protein CASK isoform X13

    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:622 → 683
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:744 → 917
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  6. XM_038651729.1 → XP_038507657.1  peripheral plasma membrane protein CASK isoform X15

    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:738 → 911
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  7. XM_038651728.1 → XP_038507656.1  peripheral plasma membrane protein CASK isoform X1

    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:738 → 911
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  8. XM_038651737.1 → XP_038507665.1  peripheral plasma membrane protein CASK isoform X20

    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:575 → 636
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:692 → 865
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  9. XM_038651731.1 → XP_038507659.1  peripheral plasma membrane protein CASK isoform X16

    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:610 → 671
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:732 → 905
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  10. XM_038651735.1 → XP_038507663.1  peripheral plasma membrane protein CASK isoform X4

    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:587 → 648
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:709 → 882
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  11. XM_038651734.1 → XP_038507662.1  peripheral plasma membrane protein CASK isoform X3

    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:593 → 654
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:710 → 883
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  12. XM_038651730.1 → XP_038507658.1  peripheral plasma membrane protein CASK isoform X2

    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:733 → 906
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    36082753..36433406 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038587210.1 → XP_038443138.1  peripheral plasma membrane protein CASK isoform X22

    UniProtKB/TrEMBL
    A0A8C0SHD4, A0A8C0SHD9, A0A8I3PPZ6, A0A8I3PQD3
    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:622 → 683
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:739 → 912
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  2. XM_038587220.1 → XP_038443148.1  peripheral plasma membrane protein CASK isoform X27

    UniProtKB/TrEMBL
    A0A8C0NDJ2
    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:587 → 648
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:709 → 882
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  3. XM_038587216.1 → XP_038443144.1  peripheral plasma membrane protein CASK isoform X26

    UniProtKB/TrEMBL
    A0A8P0NQ62
    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:599 → 660
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:721 → 894
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  4. XM_038587215.1 → XP_038443143.1  peripheral plasma membrane protein CASK isoform X25

    UniProtKB/TrEMBL
    A0A8P0TC19
    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:610 → 671
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:732 → 905
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  5. XM_038587209.1 → XP_038443137.1  peripheral plasma membrane protein CASK isoform X21

    UniProtKB/TrEMBL
    A0A8C0SHD4, A0A8I3PQD3
    Conserved Domains (6) summary
    smart00569
    Location:354 → 407
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:622 → 683
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:494 → 574
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:744 → 917
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:412 → 462
    L27; L27 domain

  6. XM_038587212.1 → XP_038443140.1  peripheral plasma membrane protein CASK isoform X23

    UniProtKB/TrEMBL
    A0A8C0SHD4, A0A8I3PQD3
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 313
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:738 → 911
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  7. XM_038587211.1 → XP_038443139.1  peripheral plasma membrane protein CASK isoform X1

    UniProtKB/TrEMBL
    A0A8C0SHD4, A0A8I3PQD3
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:738 → 911
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  8. XM_038587221.1 → XP_038443149.1  peripheral plasma membrane protein CASK isoform X28

    UniProtKB/TrEMBL
    A0A8C0NDJ2
    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:575 → 636
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:692 → 865
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  9. XM_038587214.1 → XP_038443142.1  peripheral plasma membrane protein CASK isoform X24

    UniProtKB/TrEMBL
    A0A8C0N6V9, A0A8C0SHD4, A0A8I3PNE8, A0A8I3PQD3
    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:610 → 671
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:732 → 905
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  10. XM_038587219.1 → XP_038443147.1  peripheral plasma membrane protein CASK isoform X4

    UniProtKB/TrEMBL
    A0A8P0NQ62
    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:587 → 648
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:709 → 882
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  11. XM_038587218.1 → XP_038443146.1  peripheral plasma membrane protein CASK isoform X3

    UniProtKB/TrEMBL
    A0A8C0NDJ2
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:593 → 654
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:710 → 883
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  12. XM_038587213.1 → XP_038443141.1  peripheral plasma membrane protein CASK isoform X2

    UniProtKB/TrEMBL
    A0A8C0SHD4, A0A8I3PQD3
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:733 → 906
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    23287445..23579098 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038464780.1 → XP_038320708.1  peripheral plasma membrane protein CASK isoform X29

    UniProtKB/TrEMBL
    A0A8P0NG04
    Conserved Domains (6) summary
    smart00569
    Location:325 → 378
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:593 → 654
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:465 → 545
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:715 → 888
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:383 → 433
    L27; L27 domain
    cl21453
    Location:8 → 284
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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