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FH fumarate hydratase [ Canis lupus familiaris (dog) ]

Gene ID: 480092, updated on 11-Apr-2024

Summary

Official Symbol
FHprovided by VGNC
Official Full Name
fumarate hydrataseprovided by VGNC
Primary source
VGNC:VGNC:40867
See related
Ensembl:ENSCAFG00845004348
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 7
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (32726854..32753856, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (32378016..32404992, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (32834235..32861236, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (32562040..32588973, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (32586108..32613094, complement)

Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene regulator of G protein signaling 7 Neighboring gene uncharacterized LOC119872538 Neighboring gene ribosome biogenesis protein NSA2 homolog Neighboring gene uncharacterized LOC106559037 Neighboring gene kynurenine 3-monooxygenase Neighboring gene opsin 3 Neighboring gene CHM like Rab escort protein

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables fumarate hydratase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in fumarate metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in malate metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of tricarboxylic acid cycle heteromeric enzyme complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
fumarate hydratase, mitochondrial
XP_038337246.1
XP_038398603.1
XP_038462750.1
XP_038527428.1
XP_537215.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051811.1 Reference ROS_Cfam_1.0

    Range
    32726854..32753856 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038671500.1XP_038527428.1  fumarate hydratase, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0LBE5, A0A8C0NZZ1, A0A8C0Q033, A0A8I3MXC4
    Related
    ENSCAFP00845006196.1, ENSCAFT00845007825.1
    Conserved Domains (1) summary
    PRK00485
    Location:47508
    fumC; fumarate hydratase; Reviewed

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049267.1 Alternate UMICH_Zoey_3.1

    Range
    32562040..32588973 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038481318.1XP_038337246.1  fumarate hydratase, mitochondrial

    Conserved Domains (1) summary
    PRK00485
    Location:47508
    fumC; fumarate hydratase; Reviewed

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

    Range
    32586108..32613094 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038606822.1XP_038462750.1  fumarate hydratase, mitochondrial

    Conserved Domains (1) summary
    PRK00485
    Location:47508
    fumC; fumarate hydratase; Reviewed

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

    Range
    32834235..32861236 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038542675.1XP_038398603.1  fumarate hydratase, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0LBE5, A0A8C0NZZ1, A0A8C0Q033, A0A8I3MXC4
    Conserved Domains (1) summary
    PRK00485
    Location:47508
    fumC; fumarate hydratase; Reviewed

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    32378016..32404992 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_537215.6XP_537215.1  fumarate hydratase, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0LBE5, A0A8C0NZZ1, A0A8C0Q033, A0A8I3MXC4
    Conserved Domains (1) summary
    PRK00485
    Location:47508
    fumC; fumarate hydratase; Reviewed