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STIM2 stromal interaction molecule 2 [ Canis lupus familiaris (dog) ]

Gene ID: 479120, updated on 17-Aug-2024

Summary

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Official Symbol
STIM2provided by VGNC
Official Full Name
stromal interaction molecule 2provided by VGNC
Primary source
VGNC:VGNC:46902
See related
Ensembl:ENSCAFG00845005670
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See STIM2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (84529366..84672425, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (86073946..86216661, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (84154006..84297027, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (83653235..83796214, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (83773498..83915775, complement)

Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111095306 Neighboring gene uncharacterized LOC111095307 Neighboring gene tetraspanin-3 Neighboring gene non-histone chromosomal protein HMG-14-like Neighboring gene uncharacterized LOC119871261 Neighboring gene transfer RNA serine (anticodon GCU)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of store-operated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in store-operated calcium entry IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
stromal interaction molecule 2; LOW QUALITY PROTEIN: stromal interaction molecule 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051807.1 Reference ROS_Cfam_1.0

    Range
    84529366..84672425 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038662034.1 → XP_038517962.1  stromal interaction molecule 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PMQ6
    Conserved Domains (3) summary
    cd09574
    Location:54 → 127
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:172 → 352
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:270 → 375
    SOAR; STIM1 Orai1-activating region

  2. XM_038662033.1 → XP_038517961.1  stromal interaction molecule 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PMQ6
    Related
    ENSCAFP00845007852.1, ENSCAFT00845010061.1
    Conserved Domains (3) summary
    cd09574
    Location:54 → 127
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:172 → 352
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:270 → 375
    SOAR; STIM1 Orai1-activating region

  3. XM_038662030.1 → XP_038517958.1  stromal interaction molecule 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0M2G6, A0A8C0PMQ6, A0A8I3RU98
    Related
    ENSCAFP00845007845.1, ENSCAFT00845010053.1
    Conserved Domains (3) summary
    cd09574
    Location:194 → 267
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:312 → 492
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:410 → 515
    SOAR; STIM1 Orai1-activating region

  4. XM_038662031.1 → XP_038517959.1  stromal interaction molecule 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LT40, A0A8C0PMQ6
    Conserved Domains (3) summary
    cd09574
    Location:194 → 267
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    COG1196
    Location:300 → 501
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:410 → 507
    SOAR; STIM1 Orai1-activating region

  5. XM_038662032.1 → XP_038517960.1  stromal interaction molecule 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PMQ6
    Conserved Domains (3) summary
    cd09574
    Location:100 → 173
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:218 → 398
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:316 → 421
    SOAR; STIM1 Orai1-activating region

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049263.1 Alternate UMICH_Zoey_3.1

    Range
    83653235..83796214 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038472545.1 → XP_038328473.1  stromal interaction molecule 2 isoform X4

    Conserved Domains (3) summary
    cd09574
    Location:54 → 127
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:172 → 352
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:270 → 375
    SOAR; STIM1 Orai1-activating region

  2. XM_038472544.1 → XP_038328472.1  stromal interaction molecule 2 isoform X4

    Conserved Domains (3) summary
    cd09574
    Location:54 → 127
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:172 → 352
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:270 → 375
    SOAR; STIM1 Orai1-activating region

  3. XM_038472540.1 → XP_038328468.1  stromal interaction molecule 2 isoform X1

    Conserved Domains (3) summary
    cd09574
    Location:194 → 267
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:312 → 492
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:410 → 515
    SOAR; STIM1 Orai1-activating region

  4. XM_038472541.1 → XP_038328469.1  stromal interaction molecule 2 isoform X2

    Conserved Domains (3) summary
    cd09574
    Location:194 → 267
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    COG1196
    Location:300 → 501
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:410 → 507
    SOAR; STIM1 Orai1-activating region

  5. XM_038472543.1 → XP_038328471.1  stromal interaction molecule 2 isoform X3

    Conserved Domains (3) summary
    cd09574
    Location:100 → 173
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:218 → 398
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:316 → 421
    SOAR; STIM1 Orai1-activating region

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

    Range
    83773498..83915775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038597820.1 → XP_038453748.1  LOW QUALITY PROTEIN: stromal interaction molecule 2 isoform X5

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

    Range
    84154006..84297027 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038533537.1 → XP_038389465.1  stromal interaction molecule 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PMQ6
    Conserved Domains (3) summary
    cd09574
    Location:54 → 127
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:172 → 352
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:270 → 375
    SOAR; STIM1 Orai1-activating region

  2. XM_038533536.1 → XP_038389464.1  stromal interaction molecule 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PMQ6
    Conserved Domains (3) summary
    cd09574
    Location:54 → 127
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:172 → 352
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:270 → 375
    SOAR; STIM1 Orai1-activating region

  3. XM_038533533.1 → XP_038389461.1  stromal interaction molecule 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0M2G6, A0A8C0PMQ6, A0A8I3RU98
    Conserved Domains (3) summary
    cd09574
    Location:194 → 267
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:312 → 492
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:410 → 515
    SOAR; STIM1 Orai1-activating region

  4. XM_038533534.1 → XP_038389462.1  stromal interaction molecule 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LT40, A0A8C0PMQ6
    Conserved Domains (3) summary
    cd09574
    Location:194 → 267
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    COG1196
    Location:300 → 501
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:410 → 507
    SOAR; STIM1 Orai1-activating region

  5. XM_038533535.1 → XP_038389463.1  stromal interaction molecule 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PMQ6
    Conserved Domains (3) summary
    cd09574
    Location:100 → 173
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:218 → 398
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:316 → 421
    SOAR; STIM1 Orai1-activating region

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    86073946..86216661 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038481679.1 → XP_038337607.1  stromal interaction molecule 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PMQ6
    Conserved Domains (3) summary
    cd09574
    Location:54 → 127
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:172 → 352
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:270 → 375
    SOAR; STIM1 Orai1-activating region

  2. XM_005618649.3 → XP_005618706.1  stromal interaction molecule 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PMQ6
    Conserved Domains (3) summary
    cd09574
    Location:54 → 127
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:172 → 352
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:270 → 375
    SOAR; STIM1 Orai1-activating region

  3. XM_038481645.1 → XP_038337573.1  stromal interaction molecule 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PMQ6, A0A8P0T7X1
    Conserved Domains (3) summary
    cd09574
    Location:194 → 267
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:312 → 492
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:410 → 515
    SOAR; STIM1 Orai1-activating region

  4. XM_038481655.1 → XP_038337583.1  stromal interaction molecule 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PMQ6
    Conserved Domains (3) summary
    cd09574
    Location:194 → 267
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    COG1196
    Location:300 → 501
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16533
    Location:410 → 507
    SOAR; STIM1 Orai1-activating region

  5. XM_014112647.1 → XP_013968122.1  stromal interaction molecule 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PMQ6
    Conserved Domains (3) summary
    cd09574
    Location:100 → 173
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    PRK00409
    Location:218 → 398
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    pfam16533
    Location:316 → 421
    SOAR; STIM1 Orai1-activating region
Nucleotide Protein
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