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Abd-B - Abdominal B

Enables DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including genital disc development; mating; and reproductive structure development. Located in nucleus and polytene chromosome band. Is expressed in several structures, including abdomen; epithelium; extended germ band embryo; parasegment; and reproductive system. Human ortholog(s) of this gene implicated in radioulnar synostosis. Orthologous to several human genes including HOXA11 (homeobox A11) and HOXD11 (homeobox D11). [provided by Alliance of Genome Resources, Apr 2022]

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Species Gene Architecture aa