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IMPDH2 inosine monophosphate dehydrogenase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 476630, updated on 17-Aug-2024

Summary

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Official Symbol
IMPDH2provided by VGNC
Official Full Name
inosine monophosphate dehydrogenase 2provided by VGNC
Primary source
VGNC:VGNC:42011
See related
Ensembl:ENSCAFG00845029196
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See IMPDH2 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (40493283..40498161)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (40054292..40059168)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (40543176..40548052)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (39859889..39864764)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (40263666..40268542)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene glutaminyl-tRNA synthetase 1 Neighboring gene glutamine rich 1 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 3 Neighboring gene DALR anticodon binding domain containing 3 Neighboring gene microRNA mir-191

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables IMP dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in GTP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inosine-5'-monophosphate dehydrogenase 2
Names
IMP (inosine monophosphate) dehydrogenase 2
XP_005632624.2
XP_005632625.2
XP_005632626.2
XP_038283745.1
XP_038283746.1
XP_038283747.1
XP_038283748.1
XP_038359414.1
XP_038359415.1
XP_038359416.1
XP_038359417.1
XP_038422428.1
XP_038422429.1
XP_038422430.1
XP_038422431.1
XP_038486572.1
XP_038486573.1
XP_038486574.1
XP_038486575.1
XP_850933.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    40493283..40498161
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038427817.1 → XP_038283745.1  inosine-5'-monophosphate dehydrogenase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L468
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 540
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  2. XM_038427819.1 → XP_038283747.1  inosine-5'-monophosphate dehydrogenase 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0R515
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 516
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  3. XM_038427818.1 → XP_038283746.1  inosine-5'-monophosphate dehydrogenase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L468
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 534
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  4. XM_038427820.1 → XP_038283748.1  inosine-5'-monophosphate dehydrogenase 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0R515, A0A8C0Z3I3, A0A8I3Q7R1
    Related
    ENSCAFP00845040641.1, ENSCAFT00845051796.1
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 510
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    39859889..39864764
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038503486.1 → XP_038359414.1  inosine-5'-monophosphate dehydrogenase 2 isoform X1

    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 540
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  2. XM_038503488.1 → XP_038359416.1  inosine-5'-monophosphate dehydrogenase 2 isoform X3

    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 516
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  3. XM_038503487.1 → XP_038359415.1  inosine-5'-monophosphate dehydrogenase 2 isoform X2

    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 534
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  4. XM_038503489.1 → XP_038359417.1  inosine-5'-monophosphate dehydrogenase 2 isoform X4

    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 510
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    40263666..40268542
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038630644.1 → XP_038486572.1  inosine-5'-monophosphate dehydrogenase 2 isoform X1

    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 540
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  2. XM_038630646.1 → XP_038486574.1  inosine-5'-monophosphate dehydrogenase 2 isoform X3

    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 516
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  3. XM_038630645.1 → XP_038486573.1  inosine-5'-monophosphate dehydrogenase 2 isoform X2

    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 534
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  4. XM_038630647.1 → XP_038486575.1  inosine-5'-monophosphate dehydrogenase 2 isoform X4

    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 510
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    40543176..40548052
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038566500.1 → XP_038422428.1  inosine-5'-monophosphate dehydrogenase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L468
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 540
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  2. XM_038566502.1 → XP_038422430.1  inosine-5'-monophosphate dehydrogenase 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0R515
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 516
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  3. XM_038566501.1 → XP_038422429.1  inosine-5'-monophosphate dehydrogenase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L468
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 534
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  4. XM_038566503.1 → XP_038422431.1  inosine-5'-monophosphate dehydrogenase 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0R515, A0A8C0Z3I3, A0A8I3Q7R1
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 510
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    40054292..40059168
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005632567.3 → XP_005632624.2  inosine-5'-monophosphate dehydrogenase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L468
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 540
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  2. XM_005632569.4 → XP_005632626.2  inosine-5'-monophosphate dehydrogenase 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0R515
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 516
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  3. XM_005632568.4 → XP_005632625.2  inosine-5'-monophosphate dehydrogenase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L468
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 534
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  4. XM_845840.6 → XP_850933.3  inosine-5'-monophosphate dehydrogenase 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0R515, A0A8C0Z3I3, A0A8I3Q7R1
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 510
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional
Nucleotide Protein
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