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DAG1 dystroglycan 1 [ Canis lupus familiaris (dog) ]

Gene ID: 476623, updated on 17-Aug-2024

Summary

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Official Symbol
DAG1provided by VGNC
Official Full Name
dystroglycan 1provided by VGNC
Primary source
VGNC:VGNC:39763
See related
Ensembl:ENSCAFG00845025980
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See DAG1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (40064114..40135683, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (39627718..39697490, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (40115684..40185987, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (39432635..39502839, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (39836035..39906605, complement)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene acylaminoacyl-peptide hydrolase Neighboring gene bassoon presynaptic cytomatrix protein Neighboring gene uncharacterized LOC111091329 Neighboring gene uncharacterized LOC119864692 Neighboring gene nicolin 1, tubulin polyglutamylase complex subunit Neighboring gene aminomethyltransferase Neighboring gene T cell leukemia translocation altered

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genomic organization of the dog dystroglycan gene DAG1 locus on chromosome 20q15.1-q15.2. Leeb T, et al. Genome Res, 2000 Mar. PMID 10720570, Free PMC Article
  2. Two highly polymorphic microsatellites between the canine DAG1 and BSN genes on CFA20q15.1-15.2. Leeb T, et al. Anim Genet, 2000 Oct. PMID 11105220
  3. Genomic structures and sequences of two closely linked genes (AMT, TCTA) on dog chromosome 20q15.1-->q15.2. Leeb T, et al. Cytogenet Cell Genet, 2000. PMID 10894947
  4. Partial cloning and assignment of the canine bassoon gene (BSN) to chromosome 20q15.1-->q15.2. Leeb T, et al. Cytogenet Cell Genet, 1999. PMID 10575237
  5. Cloning and characterization of the mammalian-specific nicolin 1 gene (NICN1) encoding a nuclear 24 kDa protein. Backofen B, et al. Eur J Biochem, 2002 Nov. PMID 12392556

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables laminin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in morphogenesis of an epithelium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in muscle attachment IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nerve development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of dystroglycan complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of dystrophin-associated glycoprotein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dystroglycan 1; dystroglycan
Names
dystrophin-associated glycoprotein 1
glycine cleavage system T-protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033992.1 → NP_001029164.1  dystroglycan 1 precursor

    See identical proteins and their annotated locations for NP_001029164.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ012166
    UniProtKB/Swiss-Prot
    Q9TSZ6
    UniProtKB/TrEMBL
    A0A8C0L9Q8
    Related
    ENSCAFP00845035994.1, ENSCAFT00845045847.1
    Conserved Domains (4) summary
    cd11303
    Location:59 → 160
    Dystroglycan_repeat; Cadherin-like repeat domain of alpha dystroglycan
    PRK14971
    Location:300 → 401
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam05454
    Location:603 → 892
    DAG1; Dystroglycan (Dystrophin-associated glycoprotein 1)
    pfam18424
    Location:179 → 301
    a_DG1_N2; Alpha-Dystroglycan N-terminal domain 2

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    40064114..40135683 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038426429.1 → XP_038282357.1  dystroglycan isoform X1

    UniProtKB/Swiss-Prot
    Q9TSZ6
    UniProtKB/TrEMBL
    A0A8C0L9Q8
    Conserved Domains (4) summary
    cd11303
    Location:59 → 160
    Dystroglycan_repeat; Cadherin-like repeat domain of alpha dystroglycan
    PRK14971
    Location:300 → 401
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam05454
    Location:603 → 892
    DAG1; Dystroglycan (Dystrophin-associated glycoprotein 1)
    pfam18424
    Location:179 → 301
    a_DG1_N2; Alpha-Dystroglycan N-terminal domain 2

  2. XM_038426428.1 → XP_038282356.1  dystroglycan isoform X1

    UniProtKB/Swiss-Prot
    Q9TSZ6
    UniProtKB/TrEMBL
    A0A8C0L9Q8
    Conserved Domains (4) summary
    cd11303
    Location:59 → 160
    Dystroglycan_repeat; Cadherin-like repeat domain of alpha dystroglycan
    PRK14971
    Location:300 → 401
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam05454
    Location:603 → 892
    DAG1; Dystroglycan (Dystrophin-associated glycoprotein 1)
    pfam18424
    Location:179 → 301
    a_DG1_N2; Alpha-Dystroglycan N-terminal domain 2

  3. XM_038426431.1 → XP_038282359.1  dystroglycan isoform X1

    UniProtKB/Swiss-Prot
    Q9TSZ6
    UniProtKB/TrEMBL
    A0A8C0L9Q8
    Conserved Domains (4) summary
    cd11303
    Location:59 → 160
    Dystroglycan_repeat; Cadherin-like repeat domain of alpha dystroglycan
    PRK14971
    Location:300 → 401
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam05454
    Location:603 → 892
    DAG1; Dystroglycan (Dystrophin-associated glycoprotein 1)
    pfam18424
    Location:179 → 301
    a_DG1_N2; Alpha-Dystroglycan N-terminal domain 2

  4. XM_038426432.1 → XP_038282360.1  dystroglycan isoform X1

    UniProtKB/Swiss-Prot
    Q9TSZ6
    UniProtKB/TrEMBL
    A0A8C0L9Q8
    Conserved Domains (4) summary
    cd11303
    Location:59 → 160
    Dystroglycan_repeat; Cadherin-like repeat domain of alpha dystroglycan
    PRK14971
    Location:300 → 401
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam05454
    Location:603 → 892
    DAG1; Dystroglycan (Dystrophin-associated glycoprotein 1)
    pfam18424
    Location:179 → 301
    a_DG1_N2; Alpha-Dystroglycan N-terminal domain 2

  5. XM_038426430.1 → XP_038282358.1  dystroglycan isoform X1

    UniProtKB/Swiss-Prot
    Q9TSZ6
    UniProtKB/TrEMBL
    A0A8C0L9Q8
    Conserved Domains (4) summary
    cd11303
    Location:59 → 160
    Dystroglycan_repeat; Cadherin-like repeat domain of alpha dystroglycan
    PRK14971
    Location:300 → 401
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam05454
    Location:603 → 892
    DAG1; Dystroglycan (Dystrophin-associated glycoprotein 1)
    pfam18424
    Location:179 → 301
    a_DG1_N2; Alpha-Dystroglycan N-terminal domain 2

  6. XM_038426433.1 → XP_038282361.1  dystroglycan isoform X2

    UniProtKB/TrEMBL
    A0A8C0Z1R1
    Conserved Domains (4) summary
    cd11303
    Location:428 → 532
    Dystroglycan_repeat; Cadherin-like repeat domain of alpha dystroglycan
    PRK14971
    Location:233 → 334
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam05454
    Location:536 → 825
    DAG1; Dystroglycan (Dystrophin-associated glycoprotein 1)
    pfam18424
    Location:112 → 234
    a_DG1_N2; Alpha-Dystroglycan N-terminal domain 2

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    39432635..39502839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    39836035..39906605 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    40115684..40185987 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    39627718..39697490 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9TSZ6.1 GenPept UniProtKB/Swiss-Prot:Q9TSZ6

Gene LinkOut

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