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APOC1 apolipoprotein C1 [ Canis lupus familiaris (dog) ]

Gene ID: 476437, updated on 17-Aug-2024

Summary

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Official Symbol
APOC1provided by VGNC
Official Full Name
apolipoprotein C1provided by VGNC
Primary source
VGNC:VGNC:37999
See related
Ensembl:ENSCAFG00845006666
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
Apo-CI; ApoC-I; Apo-CIB; ApoC-IB
Orthologs
human mouse all
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Genomic context

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See APOC1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (111049949..111052329, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (110001120..110003506, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (111228866..111231250, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (110724595..110726986, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (110360068..110362462, complement)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene apolipoprotein C2 Neighboring gene apolipoprotein C4 Neighboring gene apolipoprotein E Neighboring gene translocase of outer mitochondrial membrane 40

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure and expression of dog apolipoprotein A-I, E, and C-I mRNAs: implications for the evolution and functional constraints of apolipoprotein structure. Luo CC, et al. J Lipid Res, 1989 Nov. PMID 2515239
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables fatty acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phospholipase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipoprotein metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cholesterol transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of lipoprotein lipase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of very-low-density lipoprotein particle clearance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in triglyceride metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in very-low-density lipoprotein particle clearance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of high-density lipoprotein particle IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of very-low-density lipoprotein particle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
apolipoprotein C-I

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001197048.1 → NP_001183977.1  apolipoprotein C-I precursor

    See identical proteins and their annotated locations for NP_001183977.1

    Status: VALIDATED

    Source sequence(s)
    JAAUVH010000354
    UniProtKB/Swiss-Prot
    P56595
    UniProtKB/TrEMBL
    A0A8C0KHJ0
    Related
    ENSCAFP00845009224.1, ENSCAFT00845011823.1
    Conserved Domains (1) summary
    pfam04691
    Location:27 → 86
    ApoC-I; Apolipoprotein C-I (ApoC-1)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    111049949..111052329 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    110724595..110726986 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    110360068..110362462 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    111228866..111231250 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    110001120..110003506 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P56595.1 GenPept UniProtKB/Swiss-Prot:P56595

Gene LinkOut

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