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CLGN calmegin [ Canis lupus familiaris (dog) ]

Gene ID: 476076, updated on 17-Aug-2024

Summary

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Official Symbol
CLGNprovided by VGNC
Official Full Name
calmeginprovided by VGNC
Primary source
VGNC:VGNC:39336
See related
Ensembl:ENSCAFG00845021226
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See CLGN in Genome Data Viewer
Location:
chromosome: 19
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 19 NC_051823.1 (2461327..2510319)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 19 NC_006601.4 (2661232..2692491)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 19 NC_049240.1 (3133450..3164709)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 19 NC_049279.1 (2415940..2447199)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 19 NC_049760.1 (2777714..2808954)

Chromosome 19 - NC_051823.1Genomic Context describing neighboring genes Neighboring gene ELMO domain containing 2 Neighboring gene MGAT4 family member D Neighboring gene uncharacterized LOC119864430 Neighboring gene short coiled-coil protein Neighboring gene mastermind like transcriptional coactivator 3 Neighboring gene uncharacterized LOC111091089

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural basis of cyclophilin B binding by the calnexin/calreticulin P-domain. Kozlov G, et al. J Biol Chem, 2010 Nov 12. PMID 20801878, Free PMC Article
  2. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Lindblad-Toh K, et al. Nature, 2005 Dec 8. PMID 16341006
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calmegin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001313774.2 → NP_001300703.2  calmegin precursor

    Status: VALIDATED

    Source sequence(s)
    JAAUVH010000115
    UniProtKB/TrEMBL
    A0A8I3S4Z3
    Conserved Domains (1) summary
    pfam00262
    Location:62 → 429
    Calreticulin; Calreticulin family

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051823.1 Reference ROS_Cfam_1.0

    Range
    2461327..2510319
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038425563.1 → XP_038281491.1  calmegin isoform X1

    UniProtKB/TrEMBL
    A0A8C0QLN6, A0A8I3P7I8, A0A8I3S4Z3
    Related
    ENSCAFP00845029412.1, ENSCAFT00845037539.1
    Conserved Domains (1) summary
    pfam00262
    Location:72 → 439
    Calreticulin; Calreticulin family

  2. XM_038425564.1 → XP_038281492.1  calmegin isoform X2

    UniProtKB/TrEMBL
    A0A8I3S4Z3
    Related
    ENSCAFP00845029627.1, ENSCAFT00845037813.1
    Conserved Domains (1) summary
    pfam00262
    Location:62 → 429
    Calreticulin; Calreticulin family

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049279.1 Alternate UMICH_Zoey_3.1

    Range
    2415940..2447199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049760.1 Alternate UNSW_CanFamBas_1.0

    Range
    2777714..2808954
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049240.1 Alternate UU_Cfam_GSD_1.0

    Range
    3133450..3164709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006601.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    2661232..2692491
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E2RA18.2 GenPept UniProtKB/Swiss-Prot:E2RA18

Gene LinkOut

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Molecular Biology Databases
Research Materials