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SMC6 structural maintenance of chromosomes 6 [ Canis lupus familiaris (dog) ]

Gene ID: 475675, updated on 17-Aug-2024

Summary

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Official Symbol
SMC6provided by VGNC
Official Full Name
structural maintenance of chromosomes 6provided by VGNC
Primary source
VGNC:VGNC:46547
See related
Ensembl:ENSCAFG00845016537
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See SMC6 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
29
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (13269396..13337856, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (13085159..13153159, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (13165157..13233234, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (13127707..13196134, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (13138902..13207328, complement)

Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene RAD51 associated protein 2 Neighboring gene visinin like 1 Neighboring gene microRNA mir-8845 Neighboring gene dnaJ homolog subfamily A member 1-like Neighboring gene GEN1 Holliday junction 5' flap endonuclease Neighboring gene mesogenin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Smc5-Smc6 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in site of double-strand break IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
structural maintenance of chromosomes protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051821.1 Reference ROS_Cfam_1.0

    Range
    13269396..13337856 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038690761.1 → XP_038546689.1  structural maintenance of chromosomes protein 6

    UniProtKB/TrEMBL
    A0A8I3P052, A0A8I3P8X8
    Related
    ENSCAFP00845023096.1, ENSCAFT00845029385.1
    Conserved Domains (1) summary
    COG1196
    Location:53 → 1074
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. XM_038690762.1 → XP_038546690.1  structural maintenance of chromosomes protein 6

    UniProtKB/TrEMBL
    A0A8I3P052, A0A8I3P8X8
    Related
    ENSCAFP00845023330.1, ENSCAFT00845029704.1
    Conserved Domains (1) summary
    COG1196
    Location:53 → 1074
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RNA

  1. XR_005439899.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049277.1 Alternate UMICH_Zoey_3.1

    Range
    13127707..13196134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038498270.1 → XP_038354198.1  structural maintenance of chromosomes protein 6

    Conserved Domains (1) summary
    COG1196
    Location:53 → 1074
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. XM_038498271.1 → XP_038354199.1  structural maintenance of chromosomes protein 6

    Conserved Domains (1) summary
    COG1196
    Location:53 → 1074
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RNA

  1. XR_005338354.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

    Range
    13138902..13207328 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038624850.1 → XP_038480778.1  structural maintenance of chromosomes protein 6

    Conserved Domains (1) summary
    COG1196
    Location:53 → 1074
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. XM_038624851.1 → XP_038480779.1  structural maintenance of chromosomes protein 6

    Conserved Domains (1) summary
    COG1196
    Location:53 → 1074
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RNA

  1. XR_005406253.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

    Range
    13165157..13233234 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038560825.1 → XP_038416753.1  structural maintenance of chromosomes protein 6

    UniProtKB/TrEMBL
    A0A8P0P228, A0A8P0S9J7

  2. XM_038560826.1 → XP_038416754.1  structural maintenance of chromosomes protein 6

    UniProtKB/TrEMBL
    A0A8P0P228, A0A8P0S9J7

RNA

  1. XR_005372147.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    13085159..13153159 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_532882.7 → XP_532882.3  structural maintenance of chromosomes protein 6

    See identical proteins and their annotated locations for XP_532882.3

    UniProtKB/TrEMBL
    A0A8P0P228, A0A8P0S9J7
    Conserved Domains (1) summary
    cl25732
    Location:54 → 1075
    SMC_N; RecF/RecN/SMC N terminal domain

  2. XM_022404471.2 → XP_022260179.1  structural maintenance of chromosomes protein 6

    UniProtKB/TrEMBL
    A0A8P0P228, A0A8P0S9J7
    Conserved Domains (1) summary
    cl25732
    Location:54 → 1075
    SMC_N; RecF/RecN/SMC N terminal domain

RNA

  1. XR_005311071.1 RNA Sequence

Nucleotide Protein
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