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GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta [ Canis lupus familiaris (dog) ]

Gene ID: 475443, updated on 17-Aug-2024

Summary

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Official Symbol
GNPTABprovided by VGNC
Official Full Name
N-acetylglucosamine-1-phosphate transferase subunits alpha and betaprovided by VGNC
Primary source
VGNC:VGNC:41334
See related
Ensembl:ENSCAFG00845008537
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See GNPTAB in Genome Data Viewer
Location:
chromosome: 15
Exon count:
21
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (41313158..41378930, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (41027451..41092978, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (40950892..41016624, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (40567331..40640075, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (40676876..40742356, complement)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene myosin binding protein C1 Neighboring gene choline phosphotransferase 1 Neighboring gene uncharacterized LOC119868007 Neighboring gene synaptonemal complex protein 3 Neighboring gene DNA damage regulated autophagy modulator 1 Neighboring gene uncharacterized LOC119869356

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in N-glycan processing to lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta
Names
N-acetylglucosamine-1-phosphate transferase alpha and beta subunits
XP_022259125.2
XP_038303996.1
XP_038304002.1
XP_038352340.1
XP_038352341.1
XP_038352342.1
XP_038352343.1
XP_038414742.1
XP_038414743.1
XP_038414744.1
XP_038478663.1
XP_038478664.1
XP_038478665.1
XP_038544331.1
XP_038544332.1
XP_038544333.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    41313158..41378930 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038688405.1 → XP_038544333.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X3

    UniProtKB/TrEMBL
    A0A8C0RHD9, A0A8C0ST40, A0A8I3N5Z7
    Related
    ENSCAFP00845012049.1, ENSCAFT00845015512.1
    Conserved Domains (8) summary
    pfam06464
    Location:642 → 755
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:449 → 478
    Notch; LNR domain
    pfam11380
    Location:322 → 374
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:73 → 100
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:899 → 947
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1082 → 1138
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:218 → 305
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:137 → 225
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

  2. XM_038688403.1 → XP_038544331.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0LIR5, A0A8C0RHA4, A0A8C0SUH1, A0A8I3N5G9, A0A8I3N5M1
    Related
    ENSCAFP00845011784.1, ENSCAFT00845015178.1
    Conserved Domains (8) summary
    pfam06464
    Location:699 → 812
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:506 → 535
    Notch; LNR domain
    pfam11380
    Location:322 → 429
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:73 → 100
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:956 → 1004
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1139 → 1195
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:218 → 305
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:137 → 225
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

  3. XM_038688404.1 → XP_038544332.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X2

    UniProtKB/TrEMBL
    A0A8C0RHA4, A0A8I3N5M1
    Conserved Domains (8) summary
    pfam06464
    Location:653 → 766
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:460 → 489
    Notch; LNR domain
    pfam11380
    Location:276 → 383
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:27 → 54
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:910 → 958
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1093 → 1149
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:172 → 259
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:91 → 179
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    40567331..40640075 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038496413.1 → XP_038352341.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X1

    Conserved Domains (8) summary
    pfam06464
    Location:699 → 812
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:506 → 535
    Notch; LNR domain
    pfam11380
    Location:322 → 429
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:73 → 100
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:956 → 1004
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1139 → 1195
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:218 → 305
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:137 → 225
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

  2. XM_038496415.1 → XP_038352343.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X3

    Conserved Domains (8) summary
    pfam06464
    Location:642 → 755
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:449 → 478
    Notch; LNR domain
    pfam11380
    Location:322 → 374
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:73 → 100
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:899 → 947
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1082 → 1138
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:218 → 305
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:137 → 225
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

  3. XM_038496412.1 → XP_038352340.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X1

    Conserved Domains (8) summary
    pfam06464
    Location:699 → 812
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:506 → 535
    Notch; LNR domain
    pfam11380
    Location:322 → 429
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:73 → 100
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:956 → 1004
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1139 → 1195
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:218 → 305
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:137 → 225
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

  4. XM_038496414.1 → XP_038352342.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X2

    Conserved Domains (8) summary
    pfam06464
    Location:653 → 766
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:460 → 489
    Notch; LNR domain
    pfam11380
    Location:276 → 383
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:27 → 54
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:910 → 958
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1093 → 1149
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:172 → 259
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:91 → 179
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    40676876..40742356 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038622737.1 → XP_038478665.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X3

    Conserved Domains (8) summary
    pfam06464
    Location:642 → 755
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:449 → 478
    Notch; LNR domain
    pfam11380
    Location:322 → 374
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:73 → 100
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:899 → 947
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1082 → 1138
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:218 → 305
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:137 → 225
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

  2. XM_038622735.1 → XP_038478663.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X1

    Conserved Domains (8) summary
    pfam06464
    Location:699 → 812
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:506 → 535
    Notch; LNR domain
    pfam11380
    Location:322 → 429
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:73 → 100
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:956 → 1004
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1139 → 1195
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:218 → 305
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:137 → 225
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

  3. XM_038622736.1 → XP_038478664.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X2

    Conserved Domains (8) summary
    pfam06464
    Location:653 → 766
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:460 → 489
    Notch; LNR domain
    pfam11380
    Location:276 → 383
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:27 → 54
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:910 → 958
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1093 → 1149
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:172 → 259
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:91 → 179
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    40950892..41016624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038558816.1 → XP_038414744.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X3

    UniProtKB/TrEMBL
    A0A8C0RHD9, A0A8C0ST40, A0A8I3N5Z7
    Conserved Domains (8) summary
    pfam06464
    Location:642 → 755
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:449 → 478
    Notch; LNR domain
    pfam11380
    Location:322 → 374
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:73 → 100
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:899 → 947
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1082 → 1138
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:218 → 305
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:137 → 225
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

  2. XM_038558814.1 → XP_038414742.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0LIR5, A0A8C0RHA4, A0A8C0SUH1, A0A8I3N5G9, A0A8I3N5M1
    Conserved Domains (8) summary
    pfam06464
    Location:699 → 812
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:506 → 535
    Notch; LNR domain
    pfam11380
    Location:322 → 429
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:73 → 100
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:956 → 1004
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1139 → 1195
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:218 → 305
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:137 → 225
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

  3. XM_038558815.1 → XP_038414743.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X2

    UniProtKB/TrEMBL
    A0A8C0RHA4, A0A8I3N5M1
    Conserved Domains (8) summary
    pfam06464
    Location:653 → 766
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:460 → 489
    Notch; LNR domain
    pfam11380
    Location:276 → 383
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:27 → 54
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:910 → 958
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1093 → 1149
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:172 → 259
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:91 → 179
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    41027451..41092978 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038448074.1 → XP_038304002.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X3

    UniProtKB/TrEMBL
    A0A8C0RHD9, A0A8C0ST40, A0A8I3N5Z7
    Conserved Domains (8) summary
    pfam06464
    Location:642 → 755
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:449 → 478
    Notch; LNR domain
    pfam11380
    Location:322 → 374
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:73 → 100
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:899 → 947
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1082 → 1138
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:218 → 305
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:137 → 225
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

  2. XM_022403417.2 → XP_022259125.2  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0LIR5, A0A8C0RHA4, A0A8C0SUH1, A0A8I3N5G9, A0A8I3N5M1
    Conserved Domains (8) summary
    pfam06464
    Location:699 → 812
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:506 → 535
    Notch; LNR domain
    pfam11380
    Location:322 → 429
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:73 → 100
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:956 → 1004
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1139 → 1195
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:218 → 305
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:137 → 225
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins

  3. XM_038448068.1 → XP_038303996.1  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta isoform X2

    UniProtKB/TrEMBL
    A0A8C0RHA4, A0A8I3N5M1
    Conserved Domains (8) summary
    pfam06464
    Location:653 → 766
    DMAP_binding; DMAP1-binding Domain
    pfam00066
    Location:460 → 489
    Notch; LNR domain
    pfam11380
    Location:276 → 383
    Stealth_CR2; Stealth protein CR2, conserved region 2
    pfam17101
    Location:27 → 54
    Stealth_CR1; Stealth protein CR1, conserved region 1
    pfam17102
    Location:910 → 958
    Stealth_CR3; Stealth protein CR3, conserved region 3
    pfam17103
    Location:1093 → 1149
    Stealth_CR4; Stealth protein CR4, conserved region 4
    pfam18440
    Location:172 → 259
    GlcNAc-1_reg; Putative GlcNAc-1 phosphotransferase regulatory domain
    cd21599
    Location:91 → 179
    RRM1_GNPTAB; RNA recognition motif 1 (RRM1) found in N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB) and similar proteins
Nucleotide Protein
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