U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ITGB8 integrin subunit beta 8 [ Canis lupus familiaris (dog) ]

Gene ID: 475253, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
ITGB8provided by VGNC
Official Full Name
integrin subunit beta 8provided by VGNC
Primary source
VGNC:VGNC:42143
See related
Ensembl:ENSCAFG00845007494
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ITGB8 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (34291410..34369408)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (33907455..33985373)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (34421084..34499007)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (34409582..34487497)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (34110235..34188365)

Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L6-like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC102155599 Neighboring gene uncharacterized LOC111098790 Neighboring gene alcohol dehydrogenase class-3-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
integrin beta-8

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051818.1 Reference ROS_Cfam_1.0

    Range
    34291410..34369408
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038686695.1 → XP_038542623.1  integrin beta-8 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Q8B1
    Conserved Domains (2) summary
    smart00187
    Location:18 → 432
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:419 → 606
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038686693.1 → XP_038542621.1  integrin beta-8 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P6P1, A0A8C0Q8B1, A0A8I3RVE5
    Related
    ENSCAFP00845010268.1, ENSCAFT00845013214.1
    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  3. XM_038686694.1 → XP_038542622.1  integrin beta-8 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Q8B1
    Related
    ENSCAFP00845010318.1, ENSCAFT00845013294.1
    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  4. XM_038686696.1 → XP_038542624.1  integrin beta-8 isoform X4

    UniProtKB/TrEMBL
    A0A8I3N232, A0A8P0SWI9
    Related
    ENSCAFP00845010334.1, ENSCAFT00845013317.1
    Conserved Domains (2) summary
    NF033759
    Location:321 → 508
    exchanger_TraA; outer membrane exchange protein TraA
    cl00057
    Location:1 → 334
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049274.1 Alternate UMICH_Zoey_3.1

    Range
    34409582..34487497
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038494783.1 → XP_038350711.1  integrin beta-8 isoform X3

    Conserved Domains (2) summary
    smart00187
    Location:18 → 432
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:419 → 606
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038494781.1 → XP_038350709.1  integrin beta-8 isoform X1

    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  3. XM_038494782.1 → XP_038350710.1  integrin beta-8 isoform X2

    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  4. XM_038494784.1 → XP_038350712.1  integrin beta-8 isoform X4

    Conserved Domains (2) summary
    NF033759
    Location:321 → 508
    exchanger_TraA; outer membrane exchange protein TraA
    cl00057
    Location:1 → 334
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

    Range
    34110235..34188365
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038621001.1 → XP_038476929.1  integrin beta-8 isoform X3

    Conserved Domains (2) summary
    smart00187
    Location:18 → 432
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:419 → 606
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038621000.1 → XP_038476928.1  integrin beta-8 isoform X2

    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  3. XM_038620999.1 → XP_038476927.1  integrin beta-8 isoform X1

    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  4. XM_038621002.1 → XP_038476930.1  integrin beta-8 isoform X4

    Conserved Domains (2) summary
    NF033759
    Location:321 → 508
    exchanger_TraA; outer membrane exchange protein TraA
    cl00057
    Location:1 → 334
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

    Range
    34421084..34499007
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038557068.1 → XP_038412996.1  integrin beta-8 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Q8B1
    Conserved Domains (2) summary
    smart00187
    Location:18 → 432
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:419 → 606
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038557067.1 → XP_038412995.1  integrin beta-8 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Q8B1
    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  3. XM_038557065.1 → XP_038412993.1  integrin beta-8 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P6P1, A0A8C0Q8B1, A0A8I3RVE5
    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  4. XM_038557069.1 → XP_038412997.1  integrin beta-8 isoform X4

    UniProtKB/TrEMBL
    A0A8I3N232, A0A8P0SWI9
    Conserved Domains (2) summary
    NF033759
    Location:321 → 508
    exchanger_TraA; outer membrane exchange protein TraA
    cl00057
    Location:1 → 334
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    33907455..33985373
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038434587.1 → XP_038290515.1  integrin beta-8 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Q8B1
    Conserved Domains (2) summary
    smart00187
    Location:18 → 432
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:419 → 606
    exchanger_TraA; outer membrane exchange protein TraA

  2. XM_038434579.1 → XP_038290507.1  integrin beta-8 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P6P1, A0A8C0Q8B1, A0A8I3RVE5
    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  3. XM_532487.3 → XP_532487.1  integrin beta-8 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Q8B1
    Conserved Domains (2) summary
    smart00187
    Location:54 → 468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    NF033759
    Location:455 → 642
    exchanger_TraA; outer membrane exchange protein TraA

  4. XM_038434593.1 → XP_038290521.1  integrin beta-8 isoform X4

    UniProtKB/TrEMBL
    A0A8I3N232, A0A8P0SWI9
    Conserved Domains (2) summary
    NF033759
    Location:321 → 508
    exchanger_TraA; outer membrane exchange protein TraA
    cl00057
    Location:1 → 334
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials