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ADSL adenylosuccinate lyase [ Canis lupus familiaris (dog) ]

Gene ID: 474499, updated on 5-Mar-2024

Summary

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Gene symbol
ADSL
Gene description
adenylosuccinate lyase
See related
Ensembl:ENSCAFG00845020328
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See ADSL in Genome Data Viewer
Location:
chromosome: 10
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (25564321..25582627, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (24748849..24767156, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (25773156..25791459, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (25276233..25290696, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (25598775..25617073, complement)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene myocardin related transcription factor A Neighboring gene small G protein signaling modulator 3 Neighboring gene trinucleotide repeat containing adaptor 6B Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene Neighboring gene uncharacterized LOC102156637

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in 'de novo' AMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: adenylosuccinate lyase; adenylosuccinate lyase
XP_022280093.2
XP_038344468.1
XP_038406400.1
XP_038406401.1
XP_038470359.1
XP_038470360.1
XP_038535705.1
XP_038535706.1
XP_531727.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    25564321..25582627 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038679777.1 → XP_038535705.1  adenylosuccinate lyase isoform X1

    UniProtKB/TrEMBL
    A0A8C0JL16, A0A8I3P3A3, A0A8P0S762, A0A8P0SR41
    Related
    ENSCAFP00845028214.1, ENSCAFT00845036051.1
    Conserved Domains (1) summary
    cd03302
    Location:23 → 457
    Adenylsuccinate_lyase_2; Adenylsuccinate lyase (ASL)_subgroup 2

  2. XM_038679778.1 → XP_038535706.1  adenylosuccinate lyase isoform X2

    UniProtKB/TrEMBL
    A0A8P0S762
    Conserved Domains (1) summary
    cd03302
    Location:23 → 457
    Adenylsuccinate_lyase_2; Adenylsuccinate lyase (ASL)_subgroup 2

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    25276233..25290696 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038488540.1 → XP_038344468.1  LOW QUALITY PROTEIN: adenylosuccinate lyase isoform X3

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    25598775..25617073 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038614431.1 → XP_038470359.1  adenylosuccinate lyase isoform X1

    Conserved Domains (1) summary
    cd03302
    Location:23 → 457
    Adenylsuccinate_lyase_2; Adenylsuccinate lyase (ASL)_subgroup 2

  2. XM_038614432.1 → XP_038470360.1  adenylosuccinate lyase isoform X2

    Conserved Domains (1) summary
    cd03302
    Location:23 → 457
    Adenylsuccinate_lyase_2; Adenylsuccinate lyase (ASL)_subgroup 2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    25773156..25791459 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038550472.1 → XP_038406400.1  adenylosuccinate lyase isoform X1

    UniProtKB/TrEMBL
    A0A8C0JL16, A0A8I3P3A3, A0A8P0S762, A0A8P0SR41
    Conserved Domains (1) summary
    cd03302
    Location:23 → 457
    Adenylsuccinate_lyase_2; Adenylsuccinate lyase (ASL)_subgroup 2

  2. XM_038550473.1 → XP_038406401.1  adenylosuccinate lyase isoform X2

    UniProtKB/TrEMBL
    A0A8P0S762
    Conserved Domains (1) summary
    cd03302
    Location:23 → 457
    Adenylsuccinate_lyase_2; Adenylsuccinate lyase (ASL)_subgroup 2

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    24748849..24767156 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_531727.6 → XP_531727.4  adenylosuccinate lyase isoform X1

    UniProtKB/TrEMBL
    A0A8C0JL16, A0A8I3P3A3, A0A8P0S762, A0A8P0SR41
    Conserved Domains (1) summary
    cd03302
    Location:23 → 457
    Adenylsuccinate_lyase_2; Adenylsuccinate lyase (ASL)_subgroup 2

  2. XM_022424385.2 → XP_022280093.2  adenylosuccinate lyase isoform X2

    UniProtKB/TrEMBL
    A0A8P0S762
    Conserved Domains (1) summary
    cd03302
    Location:23 → 457
    Adenylsuccinate_lyase_2; Adenylsuccinate lyase (ASL)_subgroup 2
Nucleotide Protein
Heading Accession and Version

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