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GRK5 G protein-coupled receptor kinase 5 [ Pan troglodytes (chimpanzee) ]

Gene ID: 466217, updated on 10-Oct-2024

Summary

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Official Symbol
GRK5provided by VGNC
Official Full Name
G protein-coupled receptor kinase 5provided by VGNC
Primary source
VGNC:VGNC:4700
Locus tag
CK820_G0003835
See related
Ensembl:ENSPTRG00000002993
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See GRK5 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 8 NC_072406.2 (131310435..131561101)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 10 NC_072408.1 (121926108..122176034)

Chromosome 8 - NC_072406.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107966851 Neighboring gene sideroflexin 4 Neighboring gene uncharacterized LOC104008317 Neighboring gene peroxiredoxin 3 Neighboring gene uncharacterized LOC107966852 Neighboring gene uncharacterized LOC134807212 Neighboring gene regulator of G protein signaling 10 Neighboring gene uncharacterized LOC134807213 Neighboring gene TIA1 cytotoxic granule associated RNA binding protein like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G protein-coupled receptor kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
G protein-coupled receptor kinase 5
XP_016774966.1
XP_016774967.1
XP_016774968.1
XP_054516502.1
XP_063638247.1
XP_063638248.1
XP_063638249.1
XP_063638250.1
XP_063638251.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    131310435..131561101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016919477.4 → XP_016774966.1  G protein-coupled receptor kinase 5 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TJ71, A0A2J8PC35, A0A6D2WM81, H2Q2N7, K7BG59
    Related
    ENSPTRP00000005279.5
    Conserved Domains (2) summary
    cd08752
    Location:53 → 175
    RGS_GRK5; Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 5 (GRK5)
    cd05632
    Location:183 → 495
    STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5

  2. XM_016919478.4 → XP_016774967.1  G protein-coupled receptor kinase 5 isoform X2

    UniProtKB/TrEMBL
    A0A2I3TJ71
    Conserved Domains (2) summary
    cl02565
    Location:53 → 175
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl21453
    Location:183 → 465
    PKc_like; Protein Kinases, catalytic domain

  3. XM_016919479.4 → XP_016774968.1  G protein-coupled receptor kinase 5 isoform X3

    UniProtKB/TrEMBL
    A0A2I3TJ71
    Conserved Domains (2) summary
    cd08752
    Location:21 → 143
    RGS_GRK5; Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 5 (GRK5)
    cd05632
    Location:151 → 463
    STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5

  4. XM_063782177.1 → XP_063638247.1  G protein-coupled receptor kinase 5 isoform X4

  5. XM_063782180.1 → XP_063638250.1  G protein-coupled receptor kinase 5 isoform X5

    UniProtKB/TrEMBL
    G2HI44

  6. XM_063782181.1 → XP_063638251.1  G protein-coupled receptor kinase 5 isoform X5

    UniProtKB/TrEMBL
    G2HI44

  7. XM_063782179.1 → XP_063638249.1  G protein-coupled receptor kinase 5 isoform X5

    UniProtKB/TrEMBL
    G2HI44

  8. XM_063782178.1 → XP_063638248.1  G protein-coupled receptor kinase 5 isoform X5

    UniProtKB/TrEMBL
    G2HI44

  9. XM_054660527.2 → XP_054516502.1  G protein-coupled receptor kinase 5 isoform X6

Nucleotide Protein
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