GARS1 glycyl-tRNA synthetase 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: GARS1provided by VGNC
Official Full Name: glycyl-tRNA synthetase 1provided by VGNC
Primary source: VGNC:VGNC:4365
Locus tag: CK820_G0037805
See related: Ensembl:ENSPTRG00000019042
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as: GARS
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	6	NC_072404.2 (36364185..36403587)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	Unplaced Scaffold	NW_026545989.1 (459003..498403)

Chromosome 6 - NC_072404.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D7S2049E (e-PCR)
- UniSTS:151112

BARC0022 (e-PCR)
- UniSTS:255308

GARS (e-PCR)
- UniSTS:503631

RH47187 (e-PCR)
- UniSTS:9306

RH47185 (e-PCR)
- UniSTS:43417

D7S2836 (e-PCR)
- UniSTS:3558

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables glycine-tRNA ligase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in mitochondrial glycyl-tRNA aminoacylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: glycine--tRNA ligase

NP_001267407.1

EC 6.1.1.14

XP_054533482.1

EC 6.1.1.14

XP_054533483.1

EC 6.1.1.14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001280478.1 → NP_001267407.1 glycine--tRNA ligase

See identical proteins and their annotated locations for NP_001267407.1

Status: PROVISIONAL

Source sequence(s)

AK306891

UniProtKB/TrEMBL

A0A2J8KLB4, A0A5S6R8Y9, G2HJH7, H2R5E9

Related

ENSPTRP00000048086.4, ENSPTRT00000035197.7

Conserved Domains (4) summary

PLN02734
Location:61 → 724

PLN02734; glycyl-tRNA synthetase

cd00774
Location:124 → 470

GlyRS-like_core; Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3' ...

cd00858
Location:588 → 711

GlyRS_anticodon; GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is ...

cd00935
Location:64 → 114

GlyRS_RNA; GlyRS_RNA binding domain. This short RNA-binding domain is found at the N-terminus of GlyRS in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). This domain consists of a helix-turn-helix structure , which is similar to other RNA-binding ...