F11 coagulation factor XI [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: F11provided by VGNC
Official Full Name: coagulation factor XIprovided by VGNC
Primary source: VGNC:VGNC:2036
Locus tag: CK820_G0031693
See related: Ensembl:ENSPTRG00000016662
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	3	NC_072401.2 (187909166..187933948)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	4	NC_072402.1 (187868733..187893359)

Chromosome 3 - NC_072401.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH121982 (e-PCR)
- UniSTS:137750

SHGC-67651 (e-PCR)
- UniSTS:13590

SHGC4-1528 (e-PCR)
- UniSTS:76838

D4S3173 (e-PCR)
- UniSTS:80170

STS-M13142 (e-PCR)
- UniSTS:52805

SHGC-59543 (e-PCR)
- UniSTS:31352

GDB:186858 (e-PCR)
- UniSTS:155514

SHGC4-1037 (e-PCR)
- UniSTS:28807

SHGC4-289 (e-PCR)
- UniSTS:20371

G34291 (e-PCR)
- UniSTS:49818

GDB:176411 (e-PCR)
- UniSTS:154807

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: coagulation factor XI

Names: coagulation factor XI (plasma thromboplastin antecedent); platelet coagulation factor XI

XP_001165847.1

EC 3.4.21.27

XP_054539559.1

EC 3.4.21.27

XP_054539560.1

EC 3.4.21.27

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

187909166..187933948

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054683584.2 → XP_054539559.1 coagulation factor XI isoform X2
XM_001165847.7 → XP_001165847.1 coagulation factor XI isoform X1

See identical proteins and their annotated locations for XP_001165847.1

UniProtKB/TrEMBL

A0A2J8L7V6, A0A2J8L7X0, A0A6D2XY37, H2QQJ4

Related

ENSPTRP00000028578.3

Conserved Domains (2) summary

smart00223
Location:200 → 283

APPLE; APPLE domain

cd00190
Location:388 → 618

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
XM_054683585.2 → XP_054539560.1 coagulation factor XI isoform X3