TOPBP1 DNA topoisomerase II binding protein 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: TOPBP1provided by VGNC
Official Full Name: DNA topoisomerase II binding protein 1provided by VGNC
Primary source: VGNC:VGNC:8849
Locus tag: CK820_G0030016
See related: Ensembl:ENSPTRG00000015410
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 28

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	2	NC_086015.1 (136847960..136909450, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	3	NC_072401.1 (136757326..136818680, complement)

Chromosome 2 - NC_086015.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D11S2560 (e-PCR)
- UniSTS:37928

SHGC-31992 (e-PCR)
- UniSTS:74841

TOPBP1__5117 (e-PCR)
- UniSTS:466523

D15S1477 (e-PCR)
- UniSTS:474482

RH80030 (e-PCR)
- UniSTS:87680

SHGC-57698 (e-PCR)
- UniSTS:56209

D17S610 (e-PCR)
- UniSTS:46230

D11S2612 (e-PCR)
- UniSTS:70572

G20668 (e-PCR)
- UniSTS:51921

A006B05 (e-PCR)
- UniSTS:51922

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in DNA replication initiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in mitotic DNA replication checkpoint signaling	IEA Inferred from Electronic Annotation more info	PubMed
involved_in mitotic G2 DNA damage checkpoint signaling	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: DNA topoisomerase 2-binding protein 1

Names: topoisomerase (DNA) II binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

136847960..136909450 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063806230.1 → XP_063662300.1 DNA topoisomerase 2-binding protein 1 isoform X1
XM_009446506.5 → XP_009444781.4 DNA topoisomerase 2-binding protein 1 isoform X3
XM_516761.9 → XP_516761.6 DNA topoisomerase 2-binding protein 1 isoform X2