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HDAC4 histone deacetylase 4 [ Pan troglodytes (chimpanzee) ]

Gene ID: 460060, updated on 10-Oct-2024

Summary

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Official Symbol
HDAC4provided by VGNC
Official Full Name
histone deacetylase 4provided by VGNC
Primary source
VGNC:VGNC:1957
Locus tag
CK820_G0045442
See related
Ensembl:ENSPTRG00000013097
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See HDAC4 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (141237129..141596869, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (141148289..141507885, complement)

Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene twist family bHLH transcription factor 2 Neighboring gene uncharacterized LOC107973993 Neighboring gene uncharacterized LOC107973741 Neighboring gene uncharacterized LOC104005435 Neighboring gene long intergenic non-protein coding RNA 2991

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone deacetylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone deacetylase 4
XP_009442955.1
XP_009442956.1
XP_009442962.1
XP_016806335.1
XP_016806336.1
XP_016806339.1
XP_016806341.1
XP_054535595.1
XP_054535596.1
XP_054535598.1
XP_054535599.1
XP_054535601.1
XP_054535603.1
XP_063647029.1
XP_063647030.1
XP_063647031.1
XP_063647032.1
XP_063647033.1
XP_063647034.1
XP_063647035.1
XP_063647036.1
XP_063647037.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    141237129..141596869 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054679623.2 → XP_054535598.1  histone deacetylase 4 isoform X6

    UniProtKB/TrEMBL
    A0A2I3SAQ2, A0A2J8JPX1, A0A6D2VZA0

  2. XM_009444680.4 → XP_009442955.1  histone deacetylase 4 isoform X5

    See identical proteins and their annotated locations for XP_009442955.1

    UniProtKB/TrEMBL
    A0A2I3S7H7, K7CKK4
    Conserved Domains (2) summary
    cd10162
    Location:91 → 152
    ClassIIa_HDAC4_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC4, a Class IIa histone deacetylase
    cd10006
    Location:654 → 1062
    HDAC4; Histone deacetylase 4

  3. XM_016950850.4 → XP_016806339.1  histone deacetylase 4 isoform X6

    UniProtKB/TrEMBL
    A0A2I3S7H7, A0A2I3SAQ2, A0A2J8JPX1, A0A6D2VZA0
    Related
    ENSPTRP00000074061.1
    Conserved Domains (2) summary
    cd10162
    Location:91 → 152
    ClassIIa_HDAC4_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC4, a Class IIa histone deacetylase
    cd10006
    Location:649 → 1057
    HDAC4; Histone deacetylase 4

  4. XM_063790960.1 → XP_063647030.1  histone deacetylase 4 isoform X5

    UniProtKB/TrEMBL
    K7CKK4

  5. XM_054679626.2 → XP_054535601.1  histone deacetylase 4 isoform X8

  6. XM_054679628.2 → XP_054535603.1  histone deacetylase 4 isoform X11

    UniProtKB/TrEMBL
    A0A2I3TLX6

  7. XM_054679624.2 → XP_054535599.1  histone deacetylase 4 isoform X7

  8. XM_063790964.1 → XP_063647034.1  histone deacetylase 4 isoform X9

  9. XM_009444681.5 → XP_009442956.1  histone deacetylase 4 isoform X5

    See identical proteins and their annotated locations for XP_009442956.1

    UniProtKB/TrEMBL
    A0A2I3S7H7, K7CKK4
    Conserved Domains (2) summary
    cd10162
    Location:91 → 152
    ClassIIa_HDAC4_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC4, a Class IIa histone deacetylase
    cd10006
    Location:654 → 1062
    HDAC4; Histone deacetylase 4

  10. XM_063790965.1 → XP_063647035.1  histone deacetylase 4 isoform X9

  11. XM_063790963.1 → XP_063647033.1  histone deacetylase 4 isoform X8

  12. XM_063790961.1 → XP_063647031.1  histone deacetylase 4 isoform X6

    UniProtKB/TrEMBL
    A0A2I3SAQ2, A0A2J8JPX1, A0A6D2VZA0

  13. XM_063790962.1 → XP_063647032.1  histone deacetylase 4 isoform X7

  14. XM_009444687.5 → XP_009442962.1  histone deacetylase 4 isoform X10

    UniProtKB/TrEMBL
    A0A2I3S7H7
    Conserved Domains (2) summary
    cd10162
    Location:64 → 125
    ClassIIa_HDAC4_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC4, a Class IIa histone deacetylase
    cd10006
    Location:627 → 1035
    HDAC4; Histone deacetylase 4

  15. XM_054679620.2 → XP_054535595.1  histone deacetylase 4 isoform X13

  16. XM_063790959.1 → XP_063647029.1  histone deacetylase 4 isoform X3

  17. XM_016950846.4 → XP_016806335.1  histone deacetylase 4 isoform X1

    UniProtKB/TrEMBL
    A0A2I3S7H7

  18. XM_016950847.4 → XP_016806336.1  histone deacetylase 4 isoform X2

    UniProtKB/TrEMBL
    A0A2I3S7H7

  19. XM_054679621.2 → XP_054535596.1  histone deacetylase 4 isoform X4

  20. XM_063790966.1 → XP_063647036.1  histone deacetylase 4 isoform X10

  21. XM_063790967.1 → XP_063647037.1  histone deacetylase 4 isoform X12

  22. XM_016950852.4 → XP_016806341.1  histone deacetylase 4 isoform X10

    UniProtKB/TrEMBL
    A0A2I3S7H7
    Conserved Domains (2) summary
    cd10162
    Location:64 → 125
    ClassIIa_HDAC4_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC4, a Class IIa histone deacetylase
    cd10006
    Location:627 → 1035
    HDAC4; Histone deacetylase 4
Nucleotide Protein
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