DUSP18 dual specificity phosphatase 18 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: DUSP18provided by VGNC
Official Full Name: dual specificity phosphatase 18provided by VGNC
Primary source: VGNC:VGNC:12865
Locus tag: CK820_G0024527
See related: Ensembl:ENSPTRG00000014254
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	23	NC_086016.1 (32772588..32788388, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	22	NC_072420.1 (25804986..25816911, complement)

Chromosome 23 - NC_086016.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

DUSP18_1482 (e-PCR)
- UniSTS:277174

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables MAP kinase tyrosine/serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein tyrosine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in peptidyl-tyrosine dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: dual specificity protein phosphatase 18

XP_003317246.1

EC 3.1.3.16

EC 3.1.3.48

XP_016794473.1

EC 3.1.3.16

EC 3.1.3.48

XP_054531808.1

EC 3.1.3.16

EC 3.1.3.48

XP_063664210.1

EC 3.1.3.16

EC 3.1.3.48

XP_063664211.1

EC 3.1.3.16

EC 3.1.3.48

XP_063664212.1

EC 3.1.3.16

EC 3.1.3.48

XP_063664213.1

EC 3.1.3.16

EC 3.1.3.48

XP_063664214.1

EC 3.1.3.16

EC 3.1.3.48

XP_063664215.1

EC 3.1.3.16

EC 3.1.3.48

XP_063664216.1

EC 3.1.3.16

EC 3.1.3.48

XP_063664217.1

EC 3.1.3.16

EC 3.1.3.48

XP_063664218.1

EC 3.1.3.16

EC 3.1.3.48

XP_063664219.1

EC 3.1.3.16

EC 3.1.3.48

XP_063664220.1

EC 3.1.3.16

EC 3.1.3.48

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_086016.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

32772588..32788388 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063808143.1 → XP_063664213.1 dual specificity protein phosphatase 18 isoform X1

UniProtKB/TrEMBL

A0A2J8QNU0, A0A8I3B1U8, K7APU8, K7BEI4
XM_063808145.1 → XP_063664215.1 dual specificity protein phosphatase 18 isoform X1

UniProtKB/TrEMBL

A0A2J8QNU0, A0A8I3B1U8, K7APU8, K7BEI4
XM_063808147.1 → XP_063664217.1 dual specificity protein phosphatase 18 isoform X1

UniProtKB/TrEMBL

A0A2J8QNU0, A0A8I3B1U8, K7APU8, K7BEI4
XM_003317198.6 → XP_003317246.1 dual specificity protein phosphatase 18 isoform X1

See identical proteins and their annotated locations for XP_003317246.1

UniProtKB/TrEMBL

A0A2J8QNU0, A0A2J8QNU1, A0A8I3B1U8, K7APU8, K7BEI4

Conserved Domains (1) summary

cd14573
Location:19 → 176

DUSP18_21; dual specificity protein phosphatases 18 and 21
XM_063808146.1 → XP_063664216.1 dual specificity protein phosphatase 18 isoform X1

UniProtKB/TrEMBL

A0A2J8QNU0, A0A8I3B1U8, K7APU8, K7BEI4
XM_054675833.2 → XP_054531808.1 dual specificity protein phosphatase 18 isoform X1

UniProtKB/TrEMBL

A0A2J8QNU0, A0A8I3B1U8, K7APU8, K7BEI4
XM_063808144.1 → XP_063664214.1 dual specificity protein phosphatase 18 isoform X1

UniProtKB/TrEMBL

A0A2J8QNU0, A0A8I3B1U8, K7APU8, K7BEI4
XM_063808148.1 → XP_063664218.1 dual specificity protein phosphatase 18 isoform X1

UniProtKB/TrEMBL

A0A2J8QNU0, A0A8I3B1U8, K7APU8, K7BEI4
XM_063808149.1 → XP_063664219.1 dual specificity protein phosphatase 18 isoform X1

UniProtKB/TrEMBL

A0A2J8QNU0, A0A8I3B1U8, K7APU8, K7BEI4
XM_063808142.1 → XP_063664212.1 dual specificity protein phosphatase 18 isoform X1

UniProtKB/TrEMBL

A0A2J8QNU0, A0A8I3B1U8, K7APU8, K7BEI4
XM_063808150.1 → XP_063664220.1 dual specificity protein phosphatase 18 isoform X2

UniProtKB/TrEMBL

A0A2J8QNV3, A0A6D2XW87, H2QLH7
XM_063808140.1 → XP_063664210.1 dual specificity protein phosphatase 18 isoform X1

UniProtKB/TrEMBL

A0A2J8QNU0, A0A8I3B1U8, K7APU8, K7BEI4
XM_063808141.1 → XP_063664211.1 dual specificity protein phosphatase 18 isoform X1

UniProtKB/TrEMBL

A0A2J8QNU0, A0A8I3B1U8, K7APU8, K7BEI4
XM_016938984.4 → XP_016794473.1 dual specificity protein phosphatase 18 isoform X2

UniProtKB/TrEMBL

A0A2J8QNV3, A0A6D2XW87, H2QLH7

Related

ENSPTRP00000024545.4

Conserved Domains (1) summary

cl21483
Location:19 → 53

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...