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eIF4E1 - eukaryotic translation initiation factor 4E1

Enables RNA 7-methylguanosine cap binding activity; eukaryotic initiation factor 4G binding activity; and translation initiation factor activity. Involved in RNA metabolic process and translational initiation. Located in cytoplasmic ribonucleoprotein granule; cytosol; and nuclear body. Part of eukaryotic translation initiation factor 4F complex. Is active in muscle cell postsynaptic specialization. Is expressed in several structures, including embryonic/larval midgut primordium; germline cell; gonad; gut section; and somatic cell of testis. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human EIF4E (eukaryotic translation initiation factor 4E) and EIF4E1B (eukaryotic translation initiation factor 4E family member 1B). [provided by Alliance of Genome Resources, Oct 2024]

Genes similar to eIF4E1

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Species Gene Architecture aa